A9UZ24

PR
Gene name
37018
Protein name
Branched-chain-amino-acid aminotransferase
Names
Species
Monosiga brevicollis (Choanoflagellate)
KEGG Pathway
mbr:MONBRDRAFT_37018
EC number
2.6.1.42: Transaminases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-71 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A9UZ24

Entry ID Method Resolution Chain Position Source
AF-A9UZ24-F1 Predicted AlphaFoldDB

No variants for A9UZ24

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A9UZ24

No associated diseases with A9UZ24

2 regional properties for A9UZ24

Type Name Position InterPro Accession
domain AAR2, N-terminal 19 - 148 IPR033647
domain AAR2, C-terminal 205 - 359 IPR033648

Functions

Description
EC Number 2.6.1.42 Transaminases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

5 GO annotations of molecular function

Name Definition
branched-chain-amino-acid transaminase activity Catalysis of the reaction: a branched-chain amino acid + 2-oxoglutarate = L-glutamate + a 2-oxocarboxylate derived from the branched-chain amino acid.
L-isoleucine transaminase activity Catalysis of the reaction: 2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoic acid + L-glutamic acid.
L-leucine transaminase activity Catalysis of the reaction: 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamatic acid.
L-leucine:2-oxoglutarate aminotransferase activity Catalysis of the reaction: L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate.
L-valine transaminase activity Catalysis of the reaction: 2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoic acid + L-glutamatic acid.

2 GO annotations of biological process

Name Definition
leucine biosynthetic process The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid.
valine biosynthetic process The chemical reactions and pathways resulting in the formation of valine, 2-amino-3-methylbutanoic acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAAALRLTPH MRQAYPVVAA PSVARLSTLD ASKLTIETTT QPRERVEKTK LVFGHTFSDH
70 80 90 100 110 120
MLKCKWDVNE GWAAPTISPY ANLSLAPSSI VLHYAIECFE GMKAFRGDDD RIRLFRPNLN
130 140 150 160 170 180
MDRLHRSSVR LALPDFDQDE LLKCITELVI KDKDWIPAGR GYSLYLRPTH IGTAEYLGVG
190 200 210 220 230 240
KSSSSLLFCI NSPSGAYYST GFKPVSLLAD PAYVRAWPGG VGNTKGGCNY APSIYPQSQA
250 260 270 280 290 300
QAQGCQQVLW LFGEDHEVTE VGTMNLFMYW KNEQGEDELI TPPLDGTILP GVTRQSIVDM
310 320 330 340 350 360
ARGWNEFKVS ERKFNMGQVS RALKEGRVYE MFGAGTAATV CPIGQIKYLG EDLNVPLALG
370 380
NSGELTNRIW TDIFDIQYGA VEHEWAPVIA