A9TIK2

PR
Gene name
PURA2
Protein name
Adenylosuccinate synthetase 2, chloroplastic
Names
AMPSase 2, AdSS 2, IMP--aspartate ligase 2
Species
Physcomitrium patens (Spreading-leaved earth moss) (Physcomitrella patens)
KEGG Pathway
EC number
6.3.4.4: Other carbon--nitrogen ligases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-115 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A9TIK2

Entry ID Method Resolution Chain Position Source
AF-A9TIK2-F1 Predicted AlphaFoldDB

No variants for A9TIK2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A9TIK2

No associated diseases with A9TIK2

2 regional properties for A9TIK2

Type Name Position InterPro Accession
binding_site Adenylosuccinate synthase, GTP-binding site 98 - 105 IPR018220
active_site Adenylosuccinate synthase, active site 221 - 232 IPR033128

Functions

Description
EC Number 6.3.4.4 Other carbon--nitrogen ligases
Subcellular Localization
  • Plastid, chloroplast
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
chloroplast A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

3 GO annotations of molecular function

Name Definition
adenylosuccinate synthase activity Catalysis of the reaction: L-aspartate + GTP + IMP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + 3 H(+) + phosphate.
GTP binding Binding to GTP, guanosine triphosphate.
magnesium ion binding Binding to a magnesium (Mg) ion.

1 GO annotations of biological process

Name Definition
'de novo' AMP biosynthetic process The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from inosine 5'-monophosphate (IMP).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAMAAAAAVA SQGLLATSSQ QQKKSSAKLI CNAATFFSGK RLLWVKSCNN GAVGLRASGV
70 80 90 100 110 120
RCEAQAIERE AVKADAGNSR EEDAFSGLKQ VCAVLGTQWG DEGKGKLVDI LAQRFDVVAR
130 140 150 160 170 180
CQGGANAGHT IYNDKGEKFA LHLVPSGILN EKTTCVVGNG VVIHLPGFFK EIDNLESKGV
190 200 210 220 230 240
NTNGRLLVSD RAHLLFNLHQ EVDGLREAEL AGQMIGTTKR GIGPCYASKA IRNGIRVSDL
250 260 270 280 290 300
RHLDTFREKL DILYRDAAAR FKDFEYSSDE VNAEMEKYVK YAERLEPYIV DTVDYVNAAI
310 320 330 340 350 360
AEGKRILIEG GQATMLDIDF GTYPFVTSSN PSVGGICTGL GVAPNRLGDI VGVAKAYTSR
370 380 390 400 410 420
VGSGPYPTEL FGEEGDELRK AGFEWGTTTG RPRRCGWLDI VALNFVCTIN GFTAINLTKL
430 440 450 460 470 480
DVLSGLPEVK LGIAYKTPSG EKLRAFPADL SILEQVEVEY EILEGWKEDI TKVRSYDELP
490 500 510
AAAQRYVERI EELIGLPCQY IGVGPGRDAL IVKQ