Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A9SVH7

Entry ID Method Resolution Chain Position Source
AF-A9SVH7-F1 Predicted AlphaFoldDB

No variants for A9SVH7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A9SVH7

No associated diseases with A9SVH7

3 regional properties for A9SVH7

Type Name Position InterPro Accession
domain Retinoblastoma-associated protein, B-box 862 - 977 IPR002719
domain Retinoblastoma-associated protein, A-box 540 - 735 IPR002720
domain Retinoblastoma-associated protein, N-terminal 151 - 312 IPR024599

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
regulation of cell cycle Any process that modulates the rate or extent of progression through the cell cycle.
regulation of transcription by RNA polymerase II Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MERAGPVLRE VKVRSHRQSS LMSESVKQAD IEDSQVFCKQ EPVEDNIESG YETPTKSSRA
70 80 90 100 110 120
GLGDKTPNGG DIKPRKKAWS PVYLEGLEGR FREHCEVGLC LDDPTLQQAL RLFKESKPLL
130 140 150 160 170 180
LANIDSIGTS TVEDTERLWG GCVLYVVKAL SCGATVDGDK SESNAVGFTL SQLMRQTKIR
190 200 210 220 230 240
HARELDMISI CAITECLLEL PHFLVKVGPI VKQMYGDEWE KRLQVKEVQA NFVHLTALFT
250 260 270 280 290 300
YFKRVYQDFF LSPDTFTNIV SRSLSGVRDE HHVSVHMQFG WMLFLALRMH VIQQFSDLVT
310 320 330 340 350 360
CTNALMAVMF CEPLSGAWSK SNLGFCFFVF MQVILILHMP PDLRKFSLQD PVRFAKRSSE
370 380 390 400 410 420
GVDLVASLCA TYYAADEDVS SLLEKANATI SKLFGKPMKG GLAYLEGLMD KKSLAANLRM
430 440 450 460 470 480
LEKDYEDSYQ SRGGLDERMF INGEDGLLGT LSNESPRFSG SKVLFLVPSL HVDECKVKSS
490 500 510 520 530 540
FPLTNVPVYQ RKFDIMASPV RFGAFSMGAA PSSPAASPWS SPVKHMGTQG SSGGKRPPST
550 560 570 580 590 600
PVTITMTTAK WLRTVITPLA AEPSVELQLF FRSCDRDISA DVKNRAHVLL DLIFSAERGG
610 620 630 640 650 660
GWQGVAGLMD VWPEQRKLEA IKLYYKVLGA MCRSEEQRLH THNLTSLLSN ERFHRCMIAC
670 680 690 700 710 720
SAELVLATHK TVTMGFPAVL EPAGITAFDL SKVIEYFVRH EETLPRELKR HLNTIEERIL
730 740 750 760 770 780
ESMAWEKGSS MYNSLIVARP SLANEINRLC LLADPMPALE NLATQVRPAT VMHRIPGLSK
790 800 810 820 830 840
SGHSGEVACA AHTPTSASSP PQNGSSTSEA GFLSPVKDRP SAFSAFSSPM RNRLRAPLQS
850 860 870 880 890 900
AFASPQRPSP LGGGETCADT VINVFFQKAL VLAAVRIRTV CERIGQPQHL IERVYKVFQH
910 920 930 940 950 960
ALHHETSLFF NRHIDQLVLC TIYGVCKKPS YSVSGFRSYR HSCDMAMRMT LWINFQKTGG
970 980 990 1000 1010 1020
LESGDIIKFY NDVFVHVTKK FLVQVDTNSS MRSPRKAHGS DGNDGTISKL LKDEMEVIII
1030 1040 1050 1060 1070 1080
KGEAPGSPVA SIFSTFPDIS PKKVSALHNV FVSPLRSSKV DKLMSPRTRT LYACVGESTR
1090 1100 1110
DYQSPSKDLT AINNRLNKRF IAHGDLAGWT LKTDPQ