A9N2F5

PR
Gene name
pyrG
Protein name
CTP synthase
Names
Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase
Species
Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)
KEGG Pathway
spq:SPAB_03666
EC number
6.3.4.2: Other carbon--nitrogen ligases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

400-483 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A9N2F5

Entry ID Method Resolution Chain Position Source
AF-A9N2F5-F1 Predicted AlphaFoldDB

No variants for A9N2F5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A9N2F5

No associated diseases with A9N2F5

3 regional properties for A9N2F5

Type Name Position InterPro Accession
domain CTP synthase, N-terminal 5 - 266 IPR017456
domain Glutamine amidotransferase 301 - 535 IPR017926
domain CTP synthase GATase domain 290 - 533 IPR033828

Functions

Description
EC Number 6.3.4.2 Other carbon--nitrogen ligases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
CTP synthase activity Catalysis of the reaction: ATP + UTP + glutamine + H20= ADP + phosphate + CTP + glutamate.
glutaminase activity Catalysis of the reaction: L-glutamine + H2O = L-glutamate + NH3.
metal ion binding Binding to a metal ion.

2 GO annotations of biological process

Name Definition
'de novo' CTP biosynthetic process The chemical reactions and pathways resulting in the formation of cytidine 5'-triphosphate (CTP) from simpler components.
glutamine metabolic process The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTTNYIFVTG GVVSSLGKGI AAASLAAILE ARGLNVTIMK LDPYINVDPG TMSPIQHGEV
70 80 90 100 110 120
FVTEDGAETD LDLGHYERFI RTKMSRRNNF TTGRIYSDVL RKERRGDYLG ATVQVIPHIT
130 140 150 160 170 180
NAIKERVLEG GEGHDVVLVE IGGTVGDIES LPFLEAIRQL AVDIGREHAL FMHLTLVPYL
190 200 210 220 230 240
AAAGEVKTKP TQHSVKELLS IGIQPDILIC RSDRAVPANE RAKIALFCNV PEKAVISMKD
250 260 270 280 290 300
VDSIYKIPGL LKSQGLDDYI CKRFSLNCPE ANLSEWEQVI YEEANPAGEV TIGMVGKYIE
310 320 330 340 350 360
LPDAYKSVIE ALKHGGLKNR VTVNIKLIDS QDVETRGVEI LKDLDAILIP GGFGYRGVEG
370 380 390 400 410 420
KIATARYARE NNIPYLGICL GMQVALIEFA RNVAGMDNAN STEFVPDCKY PVVALITEWR
430 440 450 460 470 480
DEDGNVEVRS EKSDLGGTMR LGAQQCQLSD DSLVRQLYGA STIVERHRHR YEVNNMLLKQ
490 500 510 520 530 540
IEAAGLRVAG RSGDDQLVEI IEVPNHPWFV ACQFHPEFTS TPRDGHPLFA GFVKAANEHQ
KRQAK