A9BH73

PR
Gene name
pnp
Protein name
Polyribonucleotide nucleotidyltransferase
Names
Polynucleotide phosphorylase, PNPase
Species
Petrotoga mobilis (strain DSM 10674 / SJ95)
KEGG Pathway
pmo:Pmob_0569
EC number
2.7.7.8: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

366-445 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A9BH73

Entry ID Method Resolution Chain Position Source
AF-A9BH73-F1 Predicted AlphaFoldDB

No variants for A9BH73

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A9BH73

No associated diseases with A9BH73

9 regional properties for A9BH73

Type Name Position InterPro Accession
domain Exoribonuclease, phosphorolytic domain 1 11 - 141 IPR001247-1
domain Exoribonuclease, phosphorolytic domain 1 329 - 462 IPR001247-2
domain S1 domain 625 - 691 IPR003029
domain K Homology domain 558 - 623 IPR004087
domain K Homology domain, type 1 563 - 619 IPR004088
domain Exoribonuclease, phosphorolytic domain 2 144 - 207 IPR015847-1
domain Exoribonuclease, phosphorolytic domain 2 467 - 533 IPR015847-2
domain Polyribonucleotide nucleotidyltransferase, RNA-binding domain 249 - 326 IPR015848
domain RNA-binding domain, S1 626 - 691 IPR022967

Functions

Description
EC Number 2.7.7.8 Nucleotidyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
polyribonucleotide nucleotidyltransferase activity Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.
RNA binding Binding to an RNA molecule or a portion thereof.

2 GO annotations of biological process

Name Definition
mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKVLEKELFG RKLRIEHGKV AKQSLGSVML TFNESTILVT ADASEETVKG QDFFPLTVEF
70 80 90 100 110 120
QEKFYAVGKI PGGFIKREGK PSDEAILAAR LIDRPIRPLF PENFFNEVQV ITTVFSMLNG
130 140 150 160 170 180
DSIETWGITG ASLALNLSPI PFNGIVAGVR IGYVDGQFIA FPTQEQLKNS KIDMVVAGTK
190 200 210 220 230 240
DAVTMVEGES LEVSEEEMVE ALMFAQEKIK EIIAIEEEFL SELNIEKWEV QKEIVPEEFI
250 260 270 280 290 300
EDYLSLIDEE ELKKVLLTKG KKNRDKVISE YKKNVMKKFE EIFLEKWSVA FFEDKKRFLE
310 320 330 340 350 360
NAFEEKLQDS MRKMIINENK RVDGRTCDEI RDITCEVGLI PRVHGSALFT RGETQSLGTV
370 380 390 400 410 420
TLGAPLDVQV LDTIFSDEEK RFMLHYNFPP FSTGEVKRLR GVSRREIGHG HLAERAHKNL
430 440 450 460 470 480
IPSDEEFPYT IRVVSDILES NGSSSMASVC SASLALMDAG VPIQKHVAGI AMGLIFENDN
490 500 510 520 530 540
FVVLTDILGM EDHLGDMDFK VAGTRDGITA FQMDVKTSQV NKEVLQKALE KAKIARLKIL
550 560 570 580 590 600
DKMYETIPQP RKELSPYVPI MKVFKIPVSK IGEVIGPGGK NIKEISELYN VEVYIEDDGK
610 620 630 640 650 660
VKVTGHNANK VDEAINHIQN LIAQVEKGGI FEGTVKRVEK YGIFVEVLPG KVGMLHVSNL
670 680 690
KDKLESFKIG DKVKVEVMKV EDQGKFQLKQ LKEEN