A9BF33
Gene name |
rpoB |
Protein name |
DNA-directed RNA polymerase subunit beta |
Names |
RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta |
Species |
Petrotoga mobilis (strain DSM 10674 / SJ95) |
KEGG Pathway |
pmo:Pmob_0355 |
EC number |
2.7.7.6: Nucleotidyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A9BF33
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A9BF33-F1 | Predicted | AlphaFoldDB |
No variants for A9BF33
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A9BF33 | |||||
No associated diseases with A9BF33
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.7.6 | Nucleotidyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| DNA-directed RNA polymerase complex | A protein complex that possesses DNA-directed RNA polymerase activity. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| DNA-directed 5'-3' RNA polymerase activity | Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. |
| ribonucleoside binding | Binding to a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA-templated transcription | The synthesis of an RNA transcript from a DNA template. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNTVVREVGR | RERKFFGKVP | EKTEIYEDLV | KIQKDSFRDF | LDKKIMESIK | RYMPIKIPVK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ASGKKNKEFL | IDFVDVKFED | SSFSENECRD | KGLTYAGKAY | LKVRITDSAT | GEMIEKDDIF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LCNIPYMTER | GIFIVNGAER | VIVNQLVRSP | GVYFIKEEET | DTSKEMFIAH | FLPIKGAWLE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ILYNPNPGKE | VLQVRIDRKR | KFNFFLFLRA | LGYENDLDIL | RLFPKEIDLD | DEVELSNYNN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| CTVLSDLSFQ | ELDDMDPPRK | STYGMKLYEV | LELLKKYEIK | SVTVAHLVAE | ITLEKMKKRY |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EKEERLTSLE | AYKEIFSKLK | PTEIPRAQKA | KEEIEDMYFN | PEKFDFSQIG | RQKIQVKLRK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| AYIDYLREVE | KKDISEDMED | KIKYPIKTFA | VDKLDIILSA | RYLLHVKENI | EGLDTRDHLG |
| 430 | 440 | 450 | 460 | 470 | 480 |
| NKRVRSVGEL | MQIEFERAFS | KMIQHAPEKL | AGVQSINKIS | PQSLINSRSI | MTAFHQFFAS |
| 490 | 500 | 510 | 520 | 530 | 540 |
| SQLSQFLDQV | NPLAELTHKR | RLSAIGPGGL | KREHAKFEVR | DVHHSHYGRM | CPIETPEGAN |
| 550 | 560 | 570 | 580 | 590 | 600 |
| IGLITSMAIL | AKVDEYGFLK | TPYYRVKHAK | VDLNNIVYLS | ADEEELYRIA | PASAEIGEDG |
| 610 | 620 | 630 | 640 | 650 | 660 |
| SLVEEYIEAR | YLGKVSLFHK | DEIEYISVTP | KQIASVSAAL | IPFLEHDDAN | RALMGSNMQR |
| 670 | 680 | 690 | 700 | 710 | 720 |
| QAVPLLRPQA | PFVGTGVEWL | AARDSGYLIM | AKHKGIVDYV | DGRKIVITRL | DEENNVLKDS |
| 730 | 740 | 750 | 760 | 770 | 780 |
| NDEPLKDEYT | LLKYVRSNQD | MCINQVPIVN | VGDVVTKGQA | IADGPSMDMG | ELALGRNIFI |
| 790 | 800 | 810 | 820 | 830 | 840 |
| GFLPWEGYNF | EDAIVVSQEL | LENDAFTSIH | IEVFETKAMD | TQLGPEEITA | DIPNVKKELL |
| 850 | 860 | 870 | 880 | 890 | 900 |
| RNLDEEGIVK | IGSYVSSGDI | LVGKVTPRGE | SDTTPEEKLI | KSVFGDKGRD | IKDSSLTVPH |
| 910 | 920 | 930 | 940 | 950 | 960 |
| GIEGRVIDVQ | IFDRKDIPSL | EIGVNKYVKV | FIATKKTLQV | GDKLAGRHGN | KGVISTILNK |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| EDMPFLPDGT | PLQMLLSPLG | VPSRMNIGQV | LELHLGWLSM | LTNDYYATPI | FDGATESEIM |
| 1030 | 1040 | 1050 | 1060 | 1070 | 1080 |
| DELSKVREEH | ELYLGDDPDQ | PNGKIVLRDG | RTGEPFDFPV | AVGSMYMLKL | SHIAKDKIHA |
| 1090 | 1100 | 1110 | 1120 | 1130 | 1140 |
| RSTGPYSLIH | QQPLGGKAHF | GGQRFGEMEV | WALEAHGAAH | TLNEMLTYKS | DDIKGRNEVY |
| 1150 | 1160 | 1170 | 1180 | ||
| KAILKGENLP | EPGIPESFKV | LTKELQGLML | DIKLYDEDGN | ELDVDRL |