A9BE25

PR
Gene name
queA
Protein name
S-adenosylmethionine:tRNA ribosyltransferase-isomerase
Names
Queuosine biosynthesis protein QueA
Species
Prochlorococcus marinus (strain MIT 9211)
KEGG Pathway
pmj:P9211_04041
EC number
2.4.99.17: Transferring other glycosyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-59 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A9BE25

Entry ID Method Resolution Chain Position Source
AF-A9BE25-F1 Predicted AlphaFoldDB

No variants for A9BE25

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A9BE25

No associated diseases with A9BE25

No regional properties for A9BE25

Type Name Position InterPro Accession
No domain, repeats, and functional sites for A9BE25

Functions

Description
EC Number 2.4.99.17 Transferring other glycosyl groups
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity Catalysis of the reaction: S-adenosylmethionine + 7-(aminomethyl)-7-deazaguanosine-tRNA = adenine + methionine + epoxyqueuosine-tRNA. 7-(aminomethyl)-7-deazaguanosine-tRNA is also known as preQ1-tRNA, and epoxyqueuosine-tRNA as oQ-tRNA.

1 GO annotations of biological process

Name Definition
queuosine biosynthetic process The chemical reactions and pathways resulting in the formation of queuosines, a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLVNSQDLSL SSYDYELDSK LIAQKPLNPR HDARLMVVSK DNGPNLCVSH LKVWNLLDEL
70 80 90 100 110 120
RAGDLLVINN TRVLKARLRV RLKSGAMAEL LLLEPHGDGR WLCLAKPAKK FLPGDYVWME
130 140 150 160 170 180
ALEQESLKLQ VLTKDLETGG RIVQFPQEFS NRKSIENLLE RYGEVPLPPY IRQHDPSDAD
190 200 210 220 230 240
RYQTRFASTP GSVAAPTAGL HLSDEILNAL IQRGIEKASV TLHVGLGTFR PIEEEDLTNL
250 260 270 280 290 300
KLHSEWVEVG EEVVSAVQAC RSRGGRIFAV GTTTVRSLEA SFLLGGGSMK AFQGLVDLVI
310 320 330 340 350 360
KPGYQFGVVN GLLTNFHLPK SSLLLLVSAL IGRERLLELY QEAIERKYRF FSYGDAMFIT
370
PEAVLPGAKS PRVLQ