A9B8G1

PR
Gene name
pnp
Protein name
Polyribonucleotide nucleotidyltransferase
Names
Polynucleotide phosphorylase, PNPase
Species
Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)
KEGG Pathway
hau:Haur_3880
EC number
2.7.7.8: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

361-436 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A9B8G1

Entry ID Method Resolution Chain Position Source
AF-A9B8G1-F1 Predicted AlphaFoldDB

No variants for A9B8G1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A9B8G1

No associated diseases with A9B8G1

9 regional properties for A9B8G1

Type Name Position InterPro Accession
domain Exoribonuclease, phosphorolytic domain 1 15 - 146 IPR001247-1
domain Exoribonuclease, phosphorolytic domain 1 329 - 462 IPR001247-2
domain S1 domain 627 - 699 IPR003029
domain K Homology domain 560 - 625 IPR004087
domain K Homology domain, type 1 564 - 621 IPR004088
domain Exoribonuclease, phosphorolytic domain 2 149 - 212 IPR015847-1
domain Exoribonuclease, phosphorolytic domain 2 465 - 536 IPR015847-2
domain Polyribonucleotide nucleotidyltransferase, RNA-binding domain 244 - 326 IPR015848
domain RNA-binding domain, S1 628 - 699 IPR022967

Functions

Description
EC Number 2.7.7.8 Nucleotidyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
polyribonucleotide nucleotidyltransferase activity Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.
RNA binding Binding to an RNA molecule or a portion thereof.

2 GO annotations of biological process

Name Definition
mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSEQQVHSVT VELAGRPLTI EAGRVAQLAN GAVLVRYGDT VLLAAVTASA EPRDGIDFFP
70 80 90 100 110 120
LTVDYEEKMY AAGKIPGSFF KREGRPTETA ILTSRLTDRP LRPLFPKGYY NDVQVSITTL
130 140 150 160 170 180
STDQVNDPGP LAIIGASAAL VISDIPFAAP VGAVQMGHID GVFAVNPVMG LMENSRLDLV
190 200 210 220 230 240
VAGTSEAVMM VEASAYELTE AEMLEAVKRG HEAMQAVIQA QLELAEKCGK PKKEFVAPVV
250 260 270 280 290 300
DTSLQDEIKA WMGNRFLQAL NNSDKAAREA ATDSLRTDVL EQFSAGVAEE ELAARVKAVT
310 320 330 340 350 360
KNYDALVKDE VRASILEQGI RVDGRKVNEI RPIAVDVGVL PRVHGSGLFT RGQTQVLTVA
370 380 390 400 410 420
TLGSPGDEQR LDDLGIETTR HYMHHYNFPA FSTGEARPSR GPRRRDIGHG KLAERALVPV
430 440 450 460 470 480
LPEKDKFPYT MRLVSEVLAS NGSSSMASVC GSSLALMDAG VPIKAPVAGV AMGLITGKEA
490 500 510 520 530 540
GQFSVLTDIQ GLEDALGDMD FKVAGTTAGI TALQMDIKTT GITYEIMQQA FEQARQGRVF
550 560 570 580 590 600
ILDKMNEIIN TARNDISQFA PRIITLQIDP SKIGALIGPG GKTIRSIIEQ TGAQIDVEDD
610 620 630 640 650 660
GRVFVTTPDA DGARMAQSLI EGLTREAKVG EIFTGKVVRI MPYGAFVNVL PGKDGMVHVS
670 680 690 700 710 720
ELDEKRVENV EDVVKIGDEL TVMVIDVEPG TGKLSLSRRA ILTGETAEQR KSSSSKGGPR
730 740 750 760 770
GGGGGGDRGP RPGGDRGPRP EGDRGPRPEG DRPREGGDRG PRPGNGGNDR RGGGFRG