A9B6X4

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)
KEGG Pathway
hau:Haur_3205
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

898-1025 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A9B6X4

Entry ID Method Resolution Chain Position Source
AF-A9B6X4-F1 Predicted AlphaFoldDB

No variants for A9B6X4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A9B6X4

No associated diseases with A9B6X4

9 regional properties for A9B6X4

Type Name Position InterPro Accession
domain Helicase, C-terminal 492 - 696 IPR001650
conserved_site SEC-C motif 990 - 1007 IPR004027
domain SecA DEAD-like, N-terminal 5 - 460 IPR011115
domain SecA Wing/Scaffold 689 - 919 IPR011116
domain SecA, preprotein cross-linking domain 285 - 416 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 123 - 304 IPR014001
domain SecA motor DEAD 2 - 690 IPR014018
conserved_site SecA conserved site 558 - 573 IPR020937
domain SecA, C-terminal helicase domain 478 - 659 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MFKWLGKLLG DPNAKVVKKM QPTLDEINAL EPKMKALSDE QLREKTAELR TRFAELTKAD
70 80 90 100 110 120
REALDDRYAD ENRHDSTVEK DYQKELRVIE DAALDELLPE AFALVREASS RVIGQRHYDV
130 140 150 160 170 180
QMIGGIVLHE GRIAEMKTGE GKTLVASLPL FLNAIAGRGA HLITVNDYLA KVGGGWMGPI
190 200 210 220 230 240
FHSLGMSTGY IAHDYSAIYD PNYIDPNAKQ DDSRLVHWRP CSRREAYMAD MTYGTNNEYG
250 260 270 280 290 300
FDYLRDNMVQ HKDQCVQREL HYAIVDEVDN ILIDEARTPL IISGPAQESS DNYRRFSSLV
310 320 330 340 350 360
RGLKRSSISP DEVRKGLKDD FDGDYWIDEK SRSITLTESG LEVMEKRLNL PDGENMYDAK
370 380 390 400 410 420
NFELTHYLEN ALKAEYVFHR DVDYVVQNGE VVIVDEFTGR TMPGRRWSDG LHQAVEAKEA
430 440 450 460 470 480
VEVRRENVTL ATITFQNYFR MYNKLGGMTG TAITEAEEFS KIYNLEVVII PTNRQVVRED
490 500 510 520 530 540
YRDHIYASQK AKYNAVLREI KEMHEVGRPV LVGTTSVESS EIVSNLLKQE GLEHYLLNAK
550 560 570 580 590 600
QHEREAYIVA QAGRTGAITI ATNMAGRGTD ILLGGNPDGL IEEHLKALGT TITDATPEQL
610 620 630 640 650 660
AQAQAQAKAD VEAERKAVME AGGLHIIGTE RHEARRIDNQ LRGRAGRQGD PGSSRFFISL
670 680 690 700 710 720
EDELMTRFGR IDTIKRLMER MSDGDEELPL ESGLLDKAIE SAQTRVEGYN FDVRKHVVEY
730 740 750 760 770 780
DDVVNKQREV IYADRHAILG GEDMGDRILE MVVDEIDIHV EEFLDNRELD KPDLEGFLRQ
790 800 810 820 830 840
LYSIVPQLKA QETELAARFK GKQADEIGEI ATEVVEEAYN RLGEELATQY TTLLQRGVQP
850 860 870 880 890 900
IPGVSGPEAF FAHFERQEML GAIDREWIDY LTAVDELRQG IGNVAIAQQD PLVAFKREAF
910 920 930 940 950 960
KMFDELKGNI QNRIVYNFFT DAANWQVRLR QVELEMEARL ALAQTAGGSE NATEDAPKPA
970 980 990 1000 1010 1020
KRGVGGAARR VSNAAGQAAP ARRIVIKIGR NDPCPCDSGK KFKACHGLPG KEAELEAILA
1030
VKHTHAQAVG KK