A8YWL7

PR
Gene name
htpX
Protein name
Protease HtpX homolog
Names
Species
Lactobacillus helveticus (strain DPC 4571)
KEGG Pathway
lhe:lhv_0108
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

213-291 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A8YWL7

Entry ID Method Resolution Chain Position Source
AF-A8YWL7-F1 Predicted AlphaFoldDB

No variants for A8YWL7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A8YWL7

No associated diseases with A8YWL7

1 regional properties for A8YWL7

Type Name Position InterPro Accession
domain Peptidase M48 77 - 298 IPR001915

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
metalloendopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLYQQIARNK RKTALIMVLF VVILTLVGAG LGYLFSNRPW MGIIIALAGS LIYLLIMWQN
70 80 90 100 110 120
PANMIMSLNH AQEIQEADNP ELWHIVEDMA MVARVPMPRV YIIPDPSPNA FATGRDPNHS
130 140 150 160 170 180
AVAVTEGILQ LMNREELEGV LGHELSHVRN YDILLSTIAV VLVGVISFIS GMASRYIWFA
190 200 210 220 230 240
GGSRDSDDDR DSNAFEMIFK VVAIVFVLIL GPLSASLAQM ALSRNREYLA DASSVELTRN
250 260 270 280 290
PQGLISALRK IENSQPMKQA DRSSAGLYIE NPFHNHGLSH LFDTHPPTED RIKRLEQM