A8YUL5
Gene name |
thiI |
Protein name |
Probable tRNA sulfurtransferase |
Names |
Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase |
Species |
Lactobacillus helveticus (strain DPC 4571) |
KEGG Pathway |
lhe:lhv_0823 |
EC number |
2.8.1.4: Sulfurtransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A8YUL5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A8YUL5-F1 | Predicted | AlphaFoldDB |
No variants for A8YUL5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A8YUL5 | |||||
No associated diseases with A8YUL5
Functions
| Description | ||
|---|---|---|
| EC Number | 2.8.1.4 | Sulfurtransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| tRNA adenylyltransferase activity | Catalysis of the reaction: ATP + tRNA(n) = diphosphate + tRNA(n+1). |
| tRNA binding | Binding to a transfer RNA. |
| tRNA U4 sulfurtransferase | Catalyzes the reaction: ATP |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| thiamine biosynthetic process | +The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver. |
| thiamine diphosphate biosynthetic process | The chemical reactions and pathways resulting in the formation of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle. |
| tRNA thio-modification | The addition a sulfur atom to a nucleotide in a tRNA molecule. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEYTEVMVRY | GELSTKGKNR | KDFINRLASN | VEKVLKDLPQ | IDFHPRHDRM | HIVLNGAPFA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EVDKRLKKVF | GIQTYSPAIK | IPKTLEDIEK | TSLELMQETF | KPGMTFKVNT | KRSDHKFEYD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TNQLNNLVGD | YLFDHIDHLK | AEMKHPDLVL | RIEVRQDAVY | ISNQLLHGIG | GMPVGTAGKA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VMMLSGGIDS | PVASYLAMKR | GVDIEMVHFF | SPPYTTEKAL | AKAKELTGIL | ANYVGKINFI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AVPFAEIQET | IKEKLPEGYL | MTVQRRFMLQ | LADRIRAKRG | GLAIFNGESV | GQVASQTLQS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| MVAINDVTTT | PVIRPVATMD | KTEIIKLAED | IGTFDLSIQP | FEDCCTIFAP | PRPKTKPKLD |
| 370 | 380 | 390 | 400 | ||
| KAREYEARLD | VEGLIQRAMD | GIEVMPIYPN | EKFINDKIEE | DQDLL |