A8XV95
Gene name |
gsnl-1 |
Protein name |
Gelsolin-like protein 1 |
Names |
|
Species |
Caenorhabditis briggsae |
KEGG Pathway |
cbr:CBG_19286 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A8XV95
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A8XV95-F1 | Predicted | AlphaFoldDB |
No variants for A8XV95
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A8XV95 | |||||
No associated diseases with A8XV95
4 regional properties for A8XV95
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Gelsolin-like domain | 27 - 105 | IPR007123-1 |
| domain | Gelsolin-like domain | 146 - 203 | IPR007123-2 |
| domain | Gelsolin-like domain | 272 - 339 | IPR007123-3 |
| domain | Gelsolin-like domain | 374 - 446 | IPR007123-4 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| actin cytoskeleton | The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes. |
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| actin filament binding | Binding to an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits. |
| actin monomer binding | Binding to monomeric actin, also known as G-actin. |
| phosphatidylinositol-4,5-bisphosphate binding | Binding to phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| actin filament depolymerization | Disassembly of actin filaments by the removal of actin monomers from a filament. |
| actin filament severing | The process in which an actin filament is broken down into smaller filaments. |
| actin polymerization or depolymerization | Assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament. |
| barbed-end actin filament capping | The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits. |
| positive regulation of synapse pruning | Any process that activates or increases the frequency, rate or extent of synapse pruning. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRPTSIDPAL | AEIGKKNGLL | VWRINKFELE | PVPETEHGIF | FIGDAYIVLN | QKYEGCWDVH |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FWLGKNASTD | EIGVAAIKTV | EIDDSLGGIP | TQHREVQNYE | SPLFLSYFTD | GIRYVAGGYE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SGYNHVEDQF | KNWKPHLFHC | KGKRNVRCTE | VECEVGSLNL | GDVFILDLGK | DIYIWMPPDS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GRLERVKGMA | RAKNIADVER | MGASKVHILD | DEWDNDPTFW | SYFGGVSSVK | KVTKSKDDDD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NYWKRLSEQI | TLWKVSDVTG | AAKVTMVGQG | ENLKKELLDS | KDAFILDAIN | GGIFVWIGRE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| CTLEERSKAL | IWGQNYLKQH | HLPKWTQVTR | VLDTAESTQF | TQWFRDWVDE | KKKNTFQPLL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| FQVSDESGLL | HVEEIANFTQ | EDLDGDDVMI | LDALNSIYVW | VGSNANPNEK | KEALNTAKSY |
| 430 | 440 | 450 | 460 | 470 | |
| LEKDKLPRHK | KTSIDTIYQG | QEPPTFKKFF | PSWDDALFKN | QVRSVENMRR | LLFH |