A8WT26
Gene name |
sdhd-1 |
Protein name |
Putative succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial |
Names |
Succinate dehydrogenase complex subunit D |
Species |
Caenorhabditis briggsae |
KEGG Pathway |
cbr:CBG_02978 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A8WT26
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A8WT26-F1 | Predicted | AlphaFoldDB |
No variants for A8WT26
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A8WT26 | |||||
No associated diseases with A8WT26
No regional properties for A8WT26
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for A8WT26 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| mitochondrial inner membrane | The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. |
| mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) | A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| heme binding | Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring. |
| metal ion binding | Binding to a metal ion. |
| ubiquinone binding | Binding to ubiquinone, a quinone derivative with a tail of isoprene units. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| mitochondrial electron transport, succinate to ubiquinone | The transfer of electrons from succinate to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex II. |
| tricarboxylic acid cycle | A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAASLRHMAH | FQKALLVAKT | APRLSTIVRA | TSTLNDGASK | VPDHSMHFKL | ERLWAVGMLP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ILPASYFIHG | PVMDAVLTVA | LTLHIHWGIH | GVVYDYARPY | VIGEAAAKAA | HIGVYLITGL |
| 130 | 140 | ||||
| LLAGLLHFNT | NDVGITKAFE | LVFSL |