A8N339
Gene name |
TRM5 |
Protein name |
tRNA (guanine(37)-N1)-methyltransferase |
Names |
M1G-methyltransferase, tRNA [GM37] methyltransferase, tRNA methyltransferase 5 |
Species |
Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003) (Inky cap fungus) (Hormographiella aspergillata) |
KEGG Pathway |
cci:CC1G_06548 |
EC number |
2.1.1.228: Methyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A8N339
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A8N339-F1 | Predicted | AlphaFoldDB |
No variants for A8N339
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A8N339 | |||||
No associated diseases with A8N339
1 regional properties for A8N339
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | SAM-dependent methyltransferase TRM5/TYW2-type | 135 - 449 | IPR030382 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.1.1.228 | Methyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| mitochondrial matrix | The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| tRNA (guanine(37)-N(1))-methyltransferase activity | Catalysis of the reaction: S-adenosyl-L-methionine + guanine(37) in tRNA = N(1)-methylguanine(37) in tRNA + S-adenosyl-L-homocysteine. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTTRHLYLDT | SPPAYTGSRT | ELDKSAFHKT | LPVLAVRVRP | EKVGKFLKGD | AMKRALLDIP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KVRTVVSDPK | EEGNRLVLLR | MPNEGDIPPE | ALELIKTESN | GLTEFNVNLD | YNYWTADEIL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QSFLPEELRE | GAPSGFAMVG | HIAHLNLNEE | YLPYKYIIGQ | LILEKNNRVR | TVVNKINSID |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TQFRFFKMEL | LAGEPDYVVE | HHESDCRFMF | DFTKVYWNSR | LHTEHDRLIQ | VFQPEEVVAD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VFAGVGPFAI | PAGKKGCGVL | ANDLNPESYK | YLAINAKNNR | VDDTVKAFCE | DGREFIQKSV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SRLWEEPLPA | YTGPKQSRVQ | EEKERRRLQR | LKAEGQTVPI | PPSEKQHGRR | RISHFVMNLP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DSAISFLDAF | RGLLSGAEPA | LREQYSTMPM | VHCHCFTREV | DSRVNAEGDI | RKRVEEKLGG |
| 430 | 440 | 450 | |||
| ALTSETSFHF | VRSVAPNKDM | YCISFRLPPE | VAFGERM |