A8N1W8

PR
Gene name
MMM1
Protein name
Maintenance of mitochondrial morphology protein 1
Names
Species
Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003) (Inky cap fungus) (Hormographiella aspergillata)
KEGG Pathway
cci:CC1G_03661
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

16-101 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A8N1W8

Entry ID Method Resolution Chain Position Source
AF-A8N1W8-F1 Predicted AlphaFoldDB

No variants for A8N1W8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A8N1W8

No associated diseases with A8N1W8

4 regional properties for A8N1W8

Type Name Position InterPro Accession
domain MMM1 domain 11 - 57 IPR019411-1
domain MMM1 domain 72 - 208 IPR019411-2
domain MMM1 domain 219 - 265 IPR019411-3
domain Synaptotagmin-like mitochondrial-lipid-binding domain 73 - 281 IPR031468

Functions

Description
EC Number
Subcellular Localization
  • Endoplasmic reticulum membrane ; Single-pass type I membrane protein
  • The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions
  • These foci are often found next to mtDNA nucleoids
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
ERMES complex A protein complex that links the endoplasmic reticulum with mitochondria and may have a role in promoting exchange of calcium and phospholipids between the two organelles.
integral component of endoplasmic reticulum membrane The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
lipid binding Binding to a lipid.

3 GO annotations of biological process

Name Definition
lipid transport The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
mitochondrial genome maintenance The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome.
protein insertion into mitochondrial outer membrane The process comprising the insertion of proteins from outside the organelle into the mitochondrial outer membrane, mediated by large outer membrane translocase complexes.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTNIIFSLQP TFTQGLILGQ LSVLVLLGLI LKYLFLDSTK NPFETTSYHP QFDRKPARKQ
70 80 90 100 110 120
QAQDSQSQSE IDDVESLDWF NLLLQQVANV YRSKLRGDLA GAEGDETARQ RIEAFANKIR
130 140 150 160 170 180
PAGFLDLIKI HSVDLGAGAP TLFNARIRES DPNDPDSPPE IEFDAVYEDT LSLSLSTSYL
190 200 210 220 230 240
FNYPTASFAR LPISLTISLS QFKSSIRVIP PTPDSVAPVL TFTISPDFVL DLTTTSLMGS
250 260 270 280 290
RAKLANVPKL HELIQHQVRR VLGGRATWKV VLPGLASVAE AKQQVLKQEQ EESKRQEEA