A8J4S9

PR
Gene name
Protein name
Trehalase
Names
Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase
Species
Apis mellifera (Honeybee)
KEGG Pathway
ame:410795
EC number
3.2.1.28: Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

42-146 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A8J4S9

Entry ID Method Resolution Chain Position Source
AF-A8J4S9-F1 Predicted AlphaFoldDB

No variants for A8J4S9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A8J4S9

No associated diseases with A8J4S9

1 regional properties for A8J4S9

Type Name Position InterPro Accession
domain Casparian strip membrane protein domain 5 - 145 IPR006702

Functions

Description
EC Number 3.2.1.28 Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Subcellular Localization
  • Membrane ; Single-pass type I membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
alpha,alpha-trehalase activity Catalysis of the reaction: alpha,alpha-trehalose + H2O = 2 D-glucose.

1 GO annotations of biological process

Name Definition
trehalose metabolic process The chemical reactions and pathways involving trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MASSCSIRCG SRNILVNAAA TFLALLVVLR CFANAEKPSP CQSDVYCRGE LLHTIQMASI
70 80 90 100 110 120
YKDSKTFVDM KMKRPPDETL KSFREFMERH EQMPTRYQIE RFVNDTFDPE GSEFEDWDPD
130 140 150 160 170 180
DWTFRPKFLS RILDDDLRNF ASELNGIWKM LGRKMKDDVR VNEELYSIIY VPHPVIVPGG
190 200 210 220 230 240
RFREFYYWDS YWIVKGLLLS EMYTTVKGML TNFVSLVDKI GFIPNGGRIY YTMRSQPPML
250 260 270 280 290 300
IPMVDEYLKI THDYEWLENN LYLLEKEFDF WMTNRTVEIE VDGVNYVLAR YNEQSSGPRP
310 320 330 340 350 360
ESYKEDYLTS QSFRTNEEKD NYYSELKTAA ESGWDFSSRW FILDGTNKGN LTNLKTRYII
370 380 390 400 410 420
PVDLNSIIYR NAVLLAQYNQ RMGNESKVAY YQKRAAEWKR AIQAVLWHDE VGAWLDYDIL
430 440 450 460 470 480
NDIKRDYFYP TNILPLWTDC YDIAKREEYV SKVLKYLEKN KIMLNLGGIP TTLEHSGEQW
490 500 510 520 530 540
DYPNAWPPLQ YFVIMALNKT EDPWAQRLAY EISERWVRSN YKAYNETHSM FEKYDATVSG
550 560 570 580 590 600
GHGGGGEYEV QLGFGWSNGV IMDLLNRYGD KLTAEDRFVA TFHSNSTPQP VVVSTAGQVM
610 620
TGILALVISL AAGFIGKMRC ANNAAQ