A8IW99

PR
Gene name
CHLREDRAFT_190403
Protein name
Mitochondrial cardiolipin hydrolase
Names
Phospholipase D6 homolog, PLD 6
Species
Chlamydomonas reinhardtii (Chlamydomonas smithii)
KEGG Pathway
cre:CHLRE_13g591900v5
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-111 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A8IW99

Entry ID Method Resolution Chain Position Source
AF-A8IW99-F1 Predicted AlphaFoldDB

No variants for A8IW99

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A8IW99

No associated diseases with A8IW99

3 regional properties for A8IW99

Type Name Position InterPro Accession
domain Magnesium chelatase ChlI-like, catalytic domain 191 - 261 IPR000523
domain AAA+ ATPase domain 102 - 284 IPR003593
domain ChlI/MoxR, AAA lid domain 341 - 398 IPR041628

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion outer membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
mitochondrial outer membrane The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.

2 GO annotations of molecular function

Name Definition
endonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.
metal ion binding Binding to a metal ion.

2 GO annotations of biological process

Name Definition
lipid catabolic process The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
meiotic cell cycle Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGCASSKEEV ALTPLSDVNA AKEVADLKAQ VDQLKRQLAS AGQSAAPAAA GAVKGGVVET
70 80 90 100 110 120
LFFPDEKLPC RNNRRPGGCK RQHCEYSHTP TSLSRFLDYL GSATRTLDIC VFTITNDDIS
130 140 150 160 170 180
DVVLELHNKG VRVRIISDND QAHTQGSDID KFRQAGIAVR QDKTAAHMHH KFAIIDGRLL
190 200 210 220
LNGSFNWTRQ AVTANNENVT VLSDPKLIAS FQQQFDKLWD MFK