Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A8IHV3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A8IHV3-F1 | Predicted | AlphaFoldDB |
No variants for A8IHV3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A8IHV3 | |||||
No associated diseases with A8IHV3
5 regional properties for A8IHV3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Citrate transporter-like domain | 20 - 728 | IPR004680 |
| domain | Regulator of K+ conductance, C-terminal | 212 - 296 | IPR006037-1 |
| domain | Regulator of K+ conductance, C-terminal | 319 - 404 | IPR006037-2 |
| domain | Regulator of K+ conductance, C-terminal | 408 - 493 | IPR006037-3 |
| domain | Regulator of K+ conductance, C-terminal | 499 - 586 | IPR006037-4 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| cation transmembrane transporter activity | Enables the transfer of cation from one side of a membrane to the other. |
| symporter activity | Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| potassium ion transport | The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| sulfate transport | The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAAIGWPGIV | AIISVAISFI | IMAADWVGPD | ITFTILLSWL | TAFDGKIITV | AKAAAGYGNT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GLLTVIFLYW | VAEGVTQTGG | LELVMNYVLG | RSRSVHWALV | RSMFPVMVLS | AFLNNTPCVT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FMIPILMSWA | RRCGVPPKKL | LIPLSYAAVL | GGTCTSIGTS | TNLVIVGMQD | TRYNKQNKED |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EAKFGMFDIA | PYGVPYALMG | FVFIILTQRF | LLPGNSSRYA | KDLLIAVRVL | PSSPVVKKKL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KDSGLRTQTG | FSLAGLWRGG | AMTRQVDPDT | VLEANDILYC | AGELDVVEFV | GEEFGLGLVT |
| 310 | 320 | 330 | 340 | 350 | 360 |
| AETERALTDG | QAVGDSEATA | FHDTGASPYK | KLVQVTMTKT | ADLVGRTVRE | VSWQGRFGLI |
| 370 | 380 | 390 | 400 | 410 | 420 |
| PVAIQRGNGR | EDGRLNDVVL | AAGDVLILDT | TPHFDEARDD | FKINFEKLRF | VKDGAAKEFV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| IGVKVKKNSE | VVNKTVTAAG | LRGVPGLFVL | SVDRADGSSV | DASDYLYKIQ | PGDTLWLAAD |
| 490 | 500 | 510 | 520 | 530 | 540 |
| VGAVGFLSKF | PGLELVQQEQ | VDKTGTSILY | RHLVQAAVSH | KGPLVGKTVR | DVRFRTLYNA |
| 550 | 560 | 570 | 580 | 590 | 600 |
| AIVAVHREGV | RVPLKVQDIV | LQGGDVLLIS | CHTKWAEEHR | MDKAFVLVQA | VPDSSPPKRG |
| 610 | 620 | 630 | 640 | 650 | 660 |
| RMAIGVLLVV | GMVLTQIVGG | LKEKEYIHLW | PAAVLTAALM | LLTGCMNADQ | ARKAIMWDVY |
| 670 | 680 | 690 | 700 | 710 | 720 |
| LTIAAAFGVS | AALENTGVAG | KVANAIISIG | KSIGGDGPAL | IAIYVATAVM | SELLTNNAAG |
| 730 | 740 | 750 | 760 | 770 | 780 |
| AIMYPIAAIA | GDQLKIPAVD | ISVAIMLGAS | AGFINPFSYQ | TNLMVYAAGN | YSVREFATIG |
| 790 | 800 | 810 | 820 | 830 | 840 |
| APFQIWLMVV | ASFILCYMKQ | WKQVWIATWS | ITAFIVFVPA | LLTLLPHTVQ | NRMEAFFDRI |
| 850 | 860 | 870 | 880 | 890 | |
| AEAINPRAAL | QRRRSARAQS | FGGKAMSVGS | TESRTDGSST | PDVALTFIEM | PKMGVR |