A8IHQ3

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)
KEGG Pathway
azc:AZC_3307
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

819-924 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A8IHQ3

Entry ID Method Resolution Chain Position Source
AF-A8IHQ3-F1 Predicted AlphaFoldDB

No variants for A8IHQ3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A8IHQ3

No associated diseases with A8IHQ3

8 regional properties for A8IHQ3

Type Name Position InterPro Accession
conserved_site SEC-C motif 904 - 922 IPR004027
domain SecA DEAD-like, N-terminal 6 - 389 IPR011115
domain SecA Wing/Scaffold 629 - 839 IPR011116
domain SecA, preprotein cross-linking domain 228 - 345 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 89 - 247 IPR014001
domain SecA motor DEAD 3 - 630 IPR014018
conserved_site SecA conserved site 505 - 520 IPR020937
domain SecA, C-terminal helicase domain 407 - 600 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLGGLARKIF GSANDRRVRG YRPSVEAINK LEPELETLTD EQLRERTVMF RQQLAEGKTL
70 80 90 100 110 120
DDLLVPAFAT VREAAKRVMG MRHFDVQLIG GMVLHDAGIA EMRTGEGKTL VATLPVYLNA
130 140 150 160 170 180
LAGKGVHVVT VNDYLARRDA EWMAKVYGFL GLTTGIIVHG LDDDQRRAAY ACDVTYATNN
190 200 210 220 230 240
ELGFDYLRDN MKYERAQMVQ RPHYFAIVDE VDSILIDEAR TPLIISGPLD DRSDFYNTID
250 260 270 280 290 300
KFIPRLSKGD YEVDEKQRSV AMTEAGMEKM EQMLTEAELL KSGSLYDIEN VSIVHHVNQA
310 320 330 340 350 360
LRAHSLFQRD KDYIVRNDEV VIIDEFTGRM MPGRRYSEGL HQALEAKERV TVQPENQTLA
370 380 390 400 410 420
SITFQNYFRL YERLGGMTGT AATEAAEFAD IYKLDVVEIP TNRKVQRIDD DDEVYRTNRE
430 440 450 460 470 480
KFDAIVKLIQ ECAARKQPVL VGTTSIEKSE LLAERLKQAG MRQKDFSDRA AFTGSSDGKS
490 500 510 520 530 540
FAVLNARYHE QEAFIVAQAG VPGAVTIATN MAGRGTDIQL GGNAEMRISE ELADLPAGPE
550 560 570 580 590 600
REAAEAKIRE EIAALKQEAL AAGGLFVLGT ERHESRRIDN QLRGRSGRQG DPGHSKFFLS
610 620 630 640 650 660
LEDDLMRIFG SDRLEGMLKR LGLQEGEAII HPWINRALEK AQQKVEARNY DMRKNVLKYD
670 680 690 700 710 720
DVLNDQRKVV FEQRLELMND EDVAETVVDM RHDVITDLVA KYIPVNSYPE QWDVKGLDFA
730 740 750 760 770 780
VRDVLTLALP IEDWAKEEGI AGPEVTERII QKADEWMASK SAQYGPELMR YVEKSILLQT
790 800 810 820 830 840
LDHLWREHIA MLDHLRQVIG LRGYGQRDPL QEYKSEAFQL FSAMLGRLRE IVTAQLMRVE
850 860 870 880 890 900
IVSTPQPTEL PPMEAHHIDA STGEDELASA GAALSARPEL ALATEVPAAD RDPNDPSTWG
910 920
KVGRNEPCPC GSGKKFKHCH GRFA