A8IHK8

PR
Gene name
katG
Protein name
Catalase-peroxidase
Names
CP, Peroxidase/catalase
Species
Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)
KEGG Pathway
azc:AZC_3290
EC number
1.11.1.21: Peroxidases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-59 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A8IHK8

Entry ID Method Resolution Chain Position Source
AF-A8IHK8-F1 Predicted AlphaFoldDB

No variants for A8IHK8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A8IHK8

No associated diseases with A8IHK8

4 regional properties for A8IHK8

Type Name Position InterPro Accession
domain Haem peroxidase 87 - 439 IPR002016-1
domain Haem peroxidase 410 - 718 IPR002016-2
binding_site Peroxidases heam-ligand binding site 267 - 277 IPR019793
active_site Peroxidase, active site 106 - 117 IPR019794

Functions

Description
EC Number 1.11.1.21 Peroxidases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
catalase activity Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
metal ion binding Binding to a metal ion.

2 GO annotations of biological process

Name Definition
hydrogen peroxide catabolic process The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).
response to oxidative stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSPRARRCTD RCARMSERSM NATTETPTGK CPVAHGTGGT QNRDWWPNQL RVDLLNLHSP
70 80 90 100 110 120
KSDPLGAAFD YRAEFKKLDY EALKNDLRKL MTDSQDWWPA DFGNYGPQFV RMAWHSAGTY
130 140 150 160 170 180
RLADGRGGGG RGQQRFAPLN SWPDNVNIDK SRRLLWPIKQ KYGQKISWAD LMILTGNVAL
190 200 210 220 230 240
ETMGFRTFGF AGGREDTWEP DQDVFWGSET AWLSHRTLEK FDAPLGATEM GLIYVNPEGP
250 260 270 280 290 300
DRNGDPISAA KFIRETFARM AMNDEETVAL IGGGHTFGKT HGAAAESHKG PDPEAAALEA
310 320 330 340 350 360
QGLGWASNYG TGHGADTIGS GLEVTWTQTP AQWSNFFFEN LFKYEWVQTR SPAGAIQWEA
370 380 390 400 410 420
KDGPDIIPDA HNPEKKHKPT MLTTDLSLRF DPIYEKISRR FLENPQAFAE AFARAWFKLT
430 440 450 460 470 480
HRDLGPRSRY LGPEVPREVL LWQDPVPAVD HPLIDDADAA ALKAKVLASG LTVSELVGTA
490 500 510 520 530 540
WASASTFRGG DKRGGANGAR IRLAPQKDWA VNQPEQIDKV LKALTRIQGE FNLNASDGKK
550 560 570 580 590 600
VSLADVIVLA GNAGVEEAAK AAGHDVSVPF APGRTDASQA ETDADSFKWL EPAADGFRNY
610 620 630 640 650 660
QKDGLAVPAE VALIDKAQLL TLTAPELTVL IGGLRAININ VDGAKHGVFT DKPGALTTDF
670 680 690 700 710 720
FTNLLDMSTQ WKAAGESNDV YEGRDRQTGE LKWTGTRVDL VFGSNSILRA LAEVYAASDA
730 740
KDKFVTDFVA AWTKVMNLDR FDLA