A8HRS7
Gene name |
AZC_4089 |
Protein name |
NAD(P)H dehydrogenase (quinone) |
Names |
Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO |
Species |
Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571) |
KEGG Pathway |
azc:AZC_4089 |
EC number |
1.6.5.2: With a quinone or similar compound as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A8HRS7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A8HRS7-F1 | Predicted | AlphaFoldDB |
No variants for A8HRS7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A8HRS7 | |||||
No associated diseases with A8HRS7
5 regional properties for A8HRS7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Protein kinase domain | 14 - 270 | IPR000719 |
| domain | MIT domain | 277 - 354 | IPR007330-1 |
| domain | MIT domain | 372 - 450 | IPR007330-2 |
| active_site | Serine/threonine-protein kinase, active site | 133 - 145 | IPR008271 |
| binding_site | Protein kinase, ATP binding site | 20 - 49 | IPR017441 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.6.5.2 | With a quinone or similar compound as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
6 GO annotations of molecular function
| Name | Definition |
|---|---|
| flavin adenine dinucleotide binding | Binding to FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2. |
| FMN binding | Binding to flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes. |
| NAD binding | Binding to nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH. |
| NADH dehydrogenase (quinone) activity | Catalysis of the reaction: NADH + H+ + a quinone = NAD+ + a quinol. |
| NADP binding | Binding to nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH. |
| NADPH dehydrogenase (quinone) activity | Catalysis of the reaction: NADPH + H+ + a quinone = NADP+ + a quinol. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAKVLVLYYS | TYGHLETMAN | AVAEGARAAG | ATVDVKRVPE | TAPDEVAKAA | HFKLDQAAPV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ATIADLEHYD | AIIVGAPTRF | GRIASQMAAF | LDQAGGLWFR | GALNGKVGAA | FTSTATQHGG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QETTLFSIIT | NLLHFGMVIV | GLPYSHQGQM | SMSEIVGGAP | YGATTLAAGD | GSRQPSEIDL |
| 190 | |||||
| AGARHQGELV | AKTAAKLFG |