A8GKU0

PR
Gene name
malT
Protein name
HTH-type transcriptional regulator MalT
Names
ATP-dependent transcriptional activator MalT
Species
Serratia proteamaculans (strain 568)
KEGG Pathway
spe:Spro_4637
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

199-270 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A8GKU0

Entry ID Method Resolution Chain Position Source
AF-A8GKU0-F1 Predicted AlphaFoldDB

No variants for A8GKU0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A8GKU0

No associated diseases with A8GKU0

6 regional properties for A8GKU0

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 10 - 248 IPR003439
domain AAA+ ATPase domain 38 - 225 IPR003593
domain ABC3 transporter permease protein domain 540 - 653 IPR003838
conserved_site ABC transporter-like, conserved site 150 - 164 IPR017871
domain MacB, ATP-binding domain 10 - 226 IPR017911
domain MacB-like periplasmic core domain 284 - 500 IPR025857

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.

3 GO annotations of biological process

Name Definition
carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
positive regulation of carbohydrate metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.
positive regulation of DNA-templated transcription Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLIPSKLSRP VRLQNTVIRD RLLAKLASTA NYRLTLVNCP AGYGKTTLVA QWAAGKSDLG
70 80 90 100 110 120
WYSLDESDNQ PERFASYLIA ALQLASGGHC VKSEALSQKH QYASLSALFA QLFIELSDWH
130 140 150 160 170 180
QPLYLVIDDY HLITNDVIHE AMRFFLRHQP ENLTLILLSR TLPPLGIANL RVRDQLLEMG
190 200 210 220 230 240
TQQLAFTHQE AKQFFDCRLV SPMESQDSSR LCDEVEGWAT ALQLIALSAR QSNSSAQQSA
250 260 270 280 290 300
KRLAGLNASH LSDYLVDEVL DHVDAEARAF LLRCSVLRSM NDALIVRLTG EDNGQQRLEE
310 320 330 340 350 360
LERQGLFIHR MDDSGEWFCF HPLFATFLRQ RCQWELALEL PGLHRAAAEG WLALGYPAEA
370 380 390 400 410 420
IHHALAASDV SMLRDILLQH AWSLFHHSEL ALLEECLNAL PYERLIQNPK LALLQAWLAQ
430 440 450 460 470 480
SQHRYSEVNT LLERAEQAMR DQKIEVDRTL EAEFDALRAQ VAINAGKPEE AERLATEALK
490 500 510 520 530 540
FLPLSSYYSR IVATSVTGEV HHCKGELARA LPMMQQTEQM ARRHQAYHYA LWALLQQSEI
550 560 570 580 590 600
LIAQGFLQAA FETQDKAFEL VREQHLEQLP MHEFLLRIRS QILWSWSRLD EAEDAAREGL
610 620 630 640 650 660
KILANYQPQQ QLQCIAMLAK CSLARGDLDN ANAHMQRCEV LLHGTQYHRD WLTNADKPRV
670 680 690 700 710 720
IHWQMTGDTT AAAQWLRQTE KPGMADNHFM QGQWRNIARV QIMLGQYEEA EVVLDELNEN
730 740 750 760 770 780
ARRLRLVSDL NRNLLLSNQL YWQMERKSDA QKVLMEALSL ASRTGFISHF VIEGEAMAQQ
790 800 810 820 830 840
LRQLIQLNTL PELENHRAQR ILRDINQHHR HKFAHFDENF VDKLLTHPQV PELIRTSPLT
850 860 870 880 890 900
QREWQVLGLI YSGYSNDQIA GELAVAATTI KTHIRNLYQK LGVAHRQEAV QQAQQLLKMM
GYGA