A8GFH0

PR
Gene name
rnd
Protein name
Ribonuclease D
Names
RNase D
Species
Serratia proteamaculans (strain 568)
KEGG Pathway
spe:Spro_2759
EC number
3.1.13.5: Exoribonucleases producing 5'-phosphomonoesters
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

256-326 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A8GFH0

Entry ID Method Resolution Chain Position Source
AF-A8GFH0-F1 Predicted AlphaFoldDB

No variants for A8GFH0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A8GFH0

No associated diseases with A8GFH0

2 regional properties for A8GFH0

Type Name Position InterPro Accession
domain HRDC domain 210 - 289 IPR002121
domain 3'-5' exonuclease domain 3 - 171 IPR002562

Functions

Description
EC Number 3.1.13.5 Exoribonucleases producing 5'-phosphomonoesters
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

4 GO annotations of molecular function

Name Definition
3'-5' exonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end.
nucleic acid binding Binding to a nucleic acid.
nucleotide binding Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.
ribonuclease D activity Catalysis of the exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides.

1 GO annotations of biological process

Name Definition
tRNA 3'-end processing The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNYQLITTDA GLQQVCDQAK KHAQIALDTE FVRTRTYYPQ LGLIQLYDGE QLSLIDPLPI
70 80 90 100 110 120
KQWQPFIELL SNTQVVKFLH AGSEDLEVFL NAFKTLPTPM VDTQILAAFT GRPMSCGFAT
130 140 150 160 170 180
LVAEYMEVEL DKSEARTDWL ARPLTEKQCV YAAADVFYLL PMAKRLVQET EEAGWTAAAS
190 200 210 220 230 240
NECLLLCQRR SETLAPELAY REITNAWQLR PRQLGCLQKL AEWRLRQARE RDLAVNFVVR
250 260 270 280 290 300
EENLWQVARH MPTSLGELDS LGLSGPEIRY HGKTLVALVA EAAELEESAL PEPLPNLIDQ
310 320 330 340 350 360
PGYKKVFKEI KAAIVIASEQ SGLSSELLAS RRQINQLLNW HWKLKVGDNL PELVSGWRGD
370
LLAAPLQDIL KGY