A8G907

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Serratia proteamaculans (strain 568)
KEGG Pathway
spe:Spro_0489
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

32-328 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A8G907

Entry ID Method Resolution Chain Position Source
AF-A8G907-F1 Predicted AlphaFoldDB

No variants for A8G907

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A8G907

No associated diseases with A8G907

7 regional properties for A8G907

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 394 - 563 IPR000795
domain Small GTP-binding protein domain 398 - 553 IPR005225
domain Translation initiation factor IF-2, N-terminal 3 - 53 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 319 - 369 IPR006847-2
domain Initiation factor 2 associated domain, bacterial 58 - 96 IPR013575
domain Translation initiation factor IF- 2, domain 3 670 - 784 IPR023115
domain Translation initiation factor IF-2, domain II 570 - 663 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTTDVTVKSL AAEIQTPVDR LVQQFADAGI NKSETDSVTQ HEKEALLAHL NREHGSAPGK
70 80 90 100 110 120
LTLQRKTRST LNIPSTGGKS KSVQIEVRKK RTYVNRDTPE AQQAEAAEQA QREAEEQAQR
130 140 150 160 170 180
AAEELAKREA EAKRAAEEQA KREAAEIAKR NSAEKEKVTN QHTDEMTKPA QAEKARREAE
190 200 210 220 230 240
AAELKRKAEE EVRRKVEEDA KRVAEEARRM AEEKGEEWAA AEKASAAVET ADYHVTTSQH
250 260 270 280 290 300
ARAAEDENDA KVEGERRTRT RGGKATKQKK GNKLSESKAD REEARAVTRG GKGKRKPSTL
310 320 330 340 350 360
QQGFNKPAQV VNRDVVIGET ITVAELANKM AVKGSQVIKA MMKLGAMATI NQVIDQETAQ
370 380 390 400 410 420
LVAEEMGHKV ILRRENELEE ALMSDRDTGA AAEPRAPVVT IMGHVDHGKT SLLDYIRSTK
430 440 450 460 470 480
VAAGEAGGIT QHIGAYHVET DNGMITFLDT PGHAAFTSMR ARGAQATDIV VLVVAADDGV
490 500 510 520 530 540
MPQTIEAIQH AKAAQVPLVV AVNKIDKPEA DPDRVKQELS QYGVMPEEWG GEAQFVHVSA
550 560 570 580 590 600
KAGTGIDELL NAILLQSEVL ELKAVRSGMA SGVVIESFLD KGRGPVATVL VQEGTLNKGD
610 620 630 640 650 660
IVLCGFEYGR VRAMRDELGR EVTSAGPSIP VEILGLSSVP AAGDEATVVR DEKKAREVAL
670 680 690 700 710 720
YRQGKFREVK LARQQKSKLE NMFANMTDGE VSELNIVLKS DVQGSCEAIC ESLLKLSTDE
730 740 750 760 770 780
VKVKIVGSGV GGITETDATL AAASNAIILG FNVRADASAR RVIEAESLDL RYYSVIYNLI
790 800 810 820 830 840
DEVKQAMSGM LAPEYKQQII GLAAVRDVFK SPKFGAIAGC MVTEGNIKRH NPIRVLRDNV
850 860 870 880 890
VIYEGELESL RRFKDDVNEV RNGMECGIGV KNYNDVRVGD MIEVFEIIEI QRTIA