A8F8Y7
Gene name |
recF |
Protein name |
DNA replication and repair protein RecF |
Names |
|
Species |
Bacillus pumilus (strain SAFR-032) |
KEGG Pathway |
bpu:BPUM_0004 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A8F8Y7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A8F8Y7-F1 | Predicted | AlphaFoldDB |
No variants for A8F8Y7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A8F8Y7 | |||||
No associated diseases with A8F8Y7
3 regional properties for A8F8Y7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | RecF/RecN/SMC, N-terminal | 2 - 353 | IPR003395 |
| conserved_site | DNA-binding, RecF, conserved site | 116 - 136 | IPR018078-1 |
| conserved_site | DNA-binding, RecF, conserved site | 312 - 330 | IPR018078-2 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| single-stranded DNA binding | Binding to single-stranded DNA. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA repair | The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. |
| DNA replication | The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA. |
| SOS response | An error-prone process for repairing damaged microbial DNA. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MYIQSLALTS | YRNYEHTELQ | FDNKVNVMIG | ENAQGKTNLM | EAIYVLSMAK | SHRTSNDKEL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IRWDQDYAKI | EGRVIKKNGP | LPMQLVISKK | GKKGKVNHIE | QQKLSHYVGA | LNTIMFAPED |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LSLVKGSPQI | RRRFLDMEIG | QVSAVYLHDL | SLYQKILSQR | NHYLKQLQTR | KQTDQAMLEV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LTEQLIDAAA | KVVKRRLTFT | KQLEKWAQPL | HFGISRELET | LTLQYHTAIE | VSEASDLSKI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KNSYEESFQK | LRDREIDRGV | TLWGPHRDDL | LFFVNGRDVQ | TYGSQGQQRT | TALSLKLAEI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| DLIHEEIGEY | PILLLDDVLS | ELDDYRQSHL | LHTIQGRVQT | FVTTTSVEGI | DHATLKEAEI |
| FRVASGKVID |