Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A8EZF5

Entry ID Method Resolution Chain Position Source
AF-A8EZF5-F1 Predicted AlphaFoldDB

No variants for A8EZF5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A8EZF5

No associated diseases with A8EZF5

3 regional properties for A8EZF5

Type Name Position InterPro Accession
conserved_site Calreticulin/calnexin, conserved site 98 - 113 IPR018124-1
conserved_site Calreticulin/calnexin, conserved site 130 - 138 IPR018124-2
conserved_site Calreticulin/calnexin, conserved site 242 - 254 IPR018124-3

Functions

Description
EC Number
Subcellular Localization
  • Periplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
periplasmic space The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria).

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
cell division The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRNIIYFILL LFSCTGYALE TINIECGRAD PTPIAVNKFD ADTSTNNIVG HDVVKVISND
70 80 90 100 110 120
LKLSGLFHPI SSASFIEDKT GIEDKPLFAA WRQINASLLV NGEVKKLESG KLKISFILWD
130 140 150 160 170 180
TLLEKQLVGE ILEVPENLWR RAAHKIADKI YEKITGDAGY FDTKIVYVSE SSSLPKIKRI
190 200 210 220 230 240
ALMDYDGANN KYLTNGTSLV LTPRFARSVD KIFYVSYATK RRALIYEKDL KTGKESIVSD
250 260 270 280 290 300
FAGISFAPRF SPDGRKAVMS IAKNGSTHIY EIDLATKQLH KLTDGFGINT SPSYSPDGKK
310 320 330 340 350 360
IVYNSDRNGV PQLYIMNSDG SNVKRISFGG GSYAAPSWSP RGDYIAFTKI TRGEDGSKTF
370 380 390 400 410 420
NIGIMKAYPQ DDENSERIIT SGYLVESPCW SPNGRVIMFA KGWPSRAKVP GKNKIFAIDL
430 440
TGHNEREIIT PEDASDPEWS MVLN