Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A8CDT3

Entry ID Method Resolution Chain Position Source
AF-A8CDT3-F1 Predicted AlphaFoldDB

No variants for A8CDT3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A8CDT3

No associated diseases with A8CDT3

2 regional properties for A8CDT3

Type Name Position InterPro Accession
domain Squalene cyclase, C-terminal 414 - 751 IPR032696
domain Squalene cyclase, N-terminal 99 - 401 IPR032697

Functions

Description
EC Number 5.4.99.41 Transferring other groups
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
lipid droplet An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.

1 GO annotations of molecular function

Name Definition
lupeol synthase activity Catalysis of the reaction: (S)-2,3-epoxysqualene = lupeol. This reaction is the cyclization of (S)-2,3-epoxysqualene (2,3-oxidosqualene) to lupeol.

1 GO annotations of biological process

Name Definition
triterpenoid biosynthetic process The chemical reactions and pathways resulting in the formation of triterpenoid compounds, terpenoids with six isoprene units.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MWRLKIAEGG NNPYIYSTNN FVGRQTWEFD PEAGTPEERA QVEEARENFW RDRFLIKPSS
70 80 90 100 110 120
DLLWRFQFLS EKKFKQRIPQ VKVQDGEEIT REIATTALRR SVHLVSALQA SDGHWCAENS
130 140 150 160 170 180
GPMFFVPPMV FSLYITGHLN AVFSAEHCKE ILRYIYCHPN EDGGWGLHIE GHSAMFSTVL
190 200 210 220 230 240
NYNWLGKLGE GRDGGKDNAC ERARRRILDH GSATAISSWG KTWLAILGVY EWDGCNPMPP
250 260 270 280 290 300
EFWAFPTFFP IHPARMLCYC RLTYMAMSYL YGKKFVGPIT PLILQLREEI YNEPYDQINW
310 320 330 340 350 360
SRMRHLCAKE DNYYAHTLTQ IILWDAIYML GEPLLKRWPF NKLREKALKI TMDHIHYEDE
370 380 390 400 410 420
NSQYITIGSV EKPLLMLACW HEDPNGDAFK KHLARIPDYV WLGEDGIKIQ SFGSQVWDTS
430 440 450 460 470 480
FVLQALIASN LPSETGPTLE KGHNFIKNSQ VTQNPSGDFR RMFRHISKGS WTFSDKDHGW
490 500 510 520 530 540
QVSDCTAESL KCCLLFSMMP PELVGEKMGP QRMYDAVNVI ISLQSKNGGC SAWEPAGAGS
550 560 570 580 590 600
WMEWLNPVEF LADLVIEHEY VECTSSSLQA LVLFKKLYPE HRRKEIEIFI LNAVRFTEEI
610 620 630 640 650 660
QQPDGSWYGN WGICFLSGTW FGLKGLAAAG KTYYNCTAVR KGVEFLLQTQ RDDGGWGESY
670 680 690 700 710 720
LSCPKKIYVP LEGNRSNLVQ TALAMMGLIL GGQGERDPTP LHRAAKLLIN SQTELGDFPQ
730 740 750 760
QELSGCFMRN CMLHYSEYRD IFPTWALAEY CKLFPLPSKN D