A8AZH2
Gene name |
ackA |
Protein name |
Acetate kinase |
Names |
Acetokinase |
Species |
Streptococcus gordonii (strain Challis / ATCC 35105 / BCRC 15272 / CH1 / DL1 / V288) |
KEGG Pathway |
sgo:SGO_1916 |
EC number |
2.7.2.1: Phosphotransferases with a carboxy group as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A8AZH2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A8AZH2-F1 | Predicted | AlphaFoldDB |
No variants for A8AZH2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A8AZH2 | |||||
No associated diseases with A8AZH2
2 regional properties for A8AZH2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Aliphatic acid kinase, short-chain, conserved site | 4 - 15 | IPR023865-1 |
| conserved_site | Aliphatic acid kinase, short-chain, conserved site | 203 - 220 | IPR023865-2 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.2.1 | Phosphotransferases with a carboxy group as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| acetate kinase activity | Catalysis of the reaction: ATP + acetate = ADP + acetyl phosphate. |
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| magnesium ion binding | Binding to a magnesium (Mg) ion. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| acetyl-CoA biosynthetic process | The chemical reactions and pathways resulting in the formation of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated. |
| organic acid metabolic process | The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage. |
| phosphorylation | The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSKTIAINAG | SSSLKWQLYL | MPEEKVLAKG | LIERIGLKDS | ISTVKFDGRT | EKQVLDITDH |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TQAVKILLDD | LMRFNIIASF | DEITGVGHRV | VAGGEYFKDS | ALVDEEVIQK | VEELSLLAPL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| HNPANAAGIR | AFKELLPDIT | SVVVFDTSFH | TTMPEKAYRY | PLPTKYYKEN | KVRKYGAHGT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SHEYVAHEAA | KLLGKPLEEL | KLITCHIGNG | ASITAVDKGV | SVDTSMGFTP | LGGVMMGTRT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GDIDPAIIPY | LMQHTDDFKT | PEDISRILNR | ESGLLGVSEK | SSDMRDIHEA | MRAGDAKAQL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ANDIFVDRIQ | KYIGQYLAVL | NGADAIIFTA | GIGENSVTIR | KLVIEGISWF | GCDIDPEKNV |
| 370 | 380 | 390 | |||
| YGQYGNISTP | EAKVRVLVIP | TDEELVIARD | VERFKK |