A8AVV3
Gene name |
fmt |
Protein name |
Methionyl-tRNA formyltransferase |
Names |
|
Species |
Streptococcus gordonii (strain Challis / ATCC 35105 / BCRC 15272 / CH1 / DL1 / V288) |
KEGG Pathway |
sgo:SGO_0597 |
EC number |
2.1.2.9: Hydroxymethyl-, formyl- and related transferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A8AVV3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A8AVV3-F1 | Predicted | AlphaFoldDB |
No variants for A8AVV3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A8AVV3 | |||||
No associated diseases with A8AVV3
5 regional properties for A8AVV3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| active_site | Phosphoribosylglycinamide formyltransferase, active site | 133 - 156 | IPR001555 |
| domain | Formyl transferase, N-terminal | 4 - 179 | IPR002376 |
| domain | Formyl transferase, C-terminal | 204 - 299 | IPR005793 |
| domain | Methionyl-tRNA formyltransferase, N-terminal domain | 3 - 205 | IPR041711 |
| domain | Methionyl-tRNA formyltransferase, C-terminal domain | 208 - 292 | IPR044135 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.1.2.9 | Hydroxymethyl-, formyl- and related transferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| methionyl-tRNA formyltransferase activity | Catalysis of the reaction: 10-formyltetrahydrofolate + L-methionyl-tRNA + H2O = tetrahydrofolate + N-formylmethionyl-tRNA. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTKLIFMGTP | DFSATVLKGL | LESDQYEVLA | VVTQPDRAVG | RKKEIRITPV | KEVALSYGLP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IYQPEKLSGS | PEMEAIMNLG | ADGIVTVAFG | QFLPSKLLAR | MNFVVNVHAS | LLPKHRGGAP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IHYALIQGDK | ETGVTIMETV | KEMDAGDMIS | RRSIPITDED | NVGTLFEKLA | IVGRDLLLDT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LPAYLSGDIQ | PEAQDPSQVT | FSPNIRPEEE | RLDWNMTNRQ | LFNQIRGMNP | WPVAHTLWQG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ERFKIYEAEL | ADGEGQPGEI | LEIGKRQLLV | ATGEGALVLK | TVQPAGKPKM | TISDFLNGAG |
| 310 | |||||
| RNLAVGDKFG | N |