A8AQP0

PR
Gene name
kefB
Protein name
Glutathione-regulated potassium-efflux system protein KefB
Names
K(+)/H(+) antiporter
Species
Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)
KEGG Pathway
cko:CKO_04758
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

353-428 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A8AQP0

Entry ID Method Resolution Chain Position Source
AF-A8AQP0-F1 Predicted AlphaFoldDB

No variants for A8AQP0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A8AQP0

No associated diseases with A8AQP0

5 regional properties for A8AQP0

Type Name Position InterPro Accession
domain Aminoacyl-tRNA synthetase, class II (D/K/N) 156 - 495 IPR004364
domain OB-fold nucleic acid binding domain, AA-tRNA synthetase-type 63 - 140 IPR004365
domain Aminoacyl-tRNA synthetase, class II 178 - 493 IPR006195
domain Lysyl-tRNA synthetase, class II, C-terminal 171 - 496 IPR018149
domain Lysine-tRNA ligase, class II, N-terminal 62 - 168 IPR044136

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
glutathione-regulated potassium exporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in), where glutathione maintains the closed state.
solute:proton antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(in) = solute(in) + H+(out).

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEGSDLLTAG VMFLFAAVAA VPLASRLGIG AVLGYLLAGI AIGPWGLGFI SDVDEILHFS
70 80 90 100 110 120
ELGVVFLMFI IGLELNPSKL WQLRRSIFGV GAAQVMLSAV VLAGLLMLTD FSWQAAVIGG
130 140 150 160 170 180
IGLAMSSTAM ALQLMREKGM NRSESGQLGF SVLLFQDLAV IPALALVPLL AGSADEHFDW
190 200 210 220 230 240
IKVGMKVLAF AGMLIGGRYL LRPVFRFIAD SGVREVFTAA TLLLVLGSAL FMDALGLSMA
250 260 270 280 290 300
LGTFIAGVLL AESEYRHELE TAIDPFKGLL LGLFFISVGM SLNLGVLYTH LLWVAVSVIV
310 320 330 340 350 360
LVAVKTLVLY LLARLYGIRS SERMQFAGVL SQGGEFAFVL FSTASSQRLF QGDQMSLLLV
370 380 390 400 410 420
TVTLSMMTTP LLMKLVDKWL SRQLNGPEEE DEKPWVDDDK PQVIVVGFGR FGQVIGRLLM
430 440 450 460 470 480
ANKMRITVLE RDISAVNLMR KYGYKVYYGD ATQVELLRSA GAEAAESIVI TCNEPEDTMK
490 500 510 520 530 540
LVEICRQHFP HLHILARARG RVEAHELLQA GVTQFSRETF SSALELGRKT LVSLGMHPHQ
550 560 570 580 590 600
AQRAQLHFRR LDMRMLRELI PMHTDMVQIS RAREARRELE EIFQREMQQE RRQLDGWDEF
E