A8AIC5
Gene name |
fabA |
Protein name |
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase |
Names |
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase |
Species |
Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696) |
KEGG Pathway |
cko:CKO_02114 |
EC number |
4.2.1.59: Hydro-lyases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A8AIC5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A8AIC5-F1 | Predicted | AlphaFoldDB |
No variants for A8AIC5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A8AIC5 | |||||
No associated diseases with A8AIC5
6 regional properties for A8AIC5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | ABC transporter-like, ATP-binding domain | 6 - 259 | IPR003439-1 |
| domain | ABC transporter-like, ATP-binding domain | 324 - 550 | IPR003439-2 |
| domain | AAA+ ATPase domain | 31 - 236 | IPR003593-1 |
| domain | AAA+ ATPase domain | 348 - 522 | IPR003593-2 |
| conserved_site | ABC transporter-like, conserved site | 163 - 177 | IPR017871 |
| domain | ABC-transporter extension domain | 230 - 305 | IPR032781 |
Functions
| Description | ||
|---|---|---|
| EC Number | 4.2.1.59 | Hydro-lyases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
5 GO annotations of molecular function
| Name | Definition |
|---|---|
| (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity | Catalysis of the reaction: (3R)-3-hydroxytetradecanoyl- |
| 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity | Catalysis of the reaction: (3R)-3-hydroxydecanoyl- |
| 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity | Catalysis of the reaction: (3R)-3-hydroxyoctanoyl- |
| 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity | Catalysis of the reaction: (3R)-3-hydroxypalmitoyl- |
| trans-2-decenoyl-acyl-carrier-protein isomerase activity | Catalysis of the reaction: trans-dec-2-enoyl- |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| fatty acid biosynthetic process | The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVDKRESYTK | EDLLASGRGE | LFGAKGPQLP | APNMLMMDRV | IKMTETGGNF | DKGYVEAELD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| INPDLWFFGC | HFIGDPVMPG | CLGLDAMWQL | VGFYLGWLGG | EGKGRALGVG | EVKFTGQVLP |
| 130 | 140 | 150 | 160 | 170 | |
| SAKKVTYRIH | FKRIVNRRLI | MGLADGEVLV | DGRLIYTAND | LKVGLFQDTS | AF |