A8ABB4

PR
Gene name
rnz
Protein name
Ribonuclease Z
Names
RNase Z, tRNA 3 endonuclease, tRNase Z
Species
Ignicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125)
KEGG Pathway
iho:Igni_1037
EC number
3.1.26.11: Endoribonucleases producing 5'-phosphomonoesters
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-45 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A8ABB4

Entry ID Method Resolution Chain Position Source
AF-A8ABB4-F1 Predicted AlphaFoldDB

No variants for A8ABB4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A8ABB4

No associated diseases with A8ABB4

3 regional properties for A8ABB4

Type Name Position InterPro Accession
domain Ribosomal protein L19/L19e 3 - 149 IPR000196
conserved_site Ribosomal protein L19/L19e conserved site 7 - 26 IPR023638
domain Ribosomal protein L19, eukaryotic 4 - 167 IPR033935

Functions

Description
EC Number 3.1.26.11 Endoribonucleases producing 5'-phosphomonoesters
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
3'-tRNA processing endoribonuclease activity Catalysis of the endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.
zinc ion binding Binding to a zinc ion (Zn).

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKRARFVVLG SGAASPAPER ALPAHYFEYE GVGALLDCGE GTQFQLMKAK ISFSRIKVVF
70 80 90 100 110 120
VSHLHGDHVL GLPGLLQTMA MASRRDELLV IGPKGLKDFL LSSFELTYFY PPYPIKVVEV
130 140 150 160 170 180
LRDAEITYRN LKLKVFPVNH TVPAFGVSVE TASKRKVRAD VLEREGLPKR LWGRLQRGED
190 200 210 220 230 240
VVWEGRVFKY EDFTFEGERI KVVYSGDTAP CERLVEEAEG ADLLVHEATF TKELKEEAHD
250 260 270 280 290
RGHSTAEDAA TAAARAGVKQ LLMVHFSARY KDLRRHLEEA RRVFPRSYAA EDLTKVVILK