Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A7ZC69

Entry ID Method Resolution Chain Position Source
AF-A7ZC69-F1 Predicted AlphaFoldDB

No variants for A7ZC69

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A7ZC69

No associated diseases with A7ZC69

6 regional properties for A7ZC69

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 384 - 553 IPR000795
domain Small GTP-binding protein domain 388 - 543 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 51 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 305 - 356 IPR006847-2
domain Translation initiation factor IF- 2, domain 3 659 - 775 IPR023115
domain Translation initiation factor IF-2, domain II 560 - 654 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSNVRISEIA NELGYPSKEI VEKAQELGLK VKTHSNAVSL EEAEAIYEYV QTGVIPDKFK
70 80 90 100 110 120
KKKSEPKAKK EPKKETEKEP AKKEEKPKTE PKKAATKAEP KPEKAKAEPK KEAQISEEKP
130 140 150 160 170 180
KTEPKKEEPV KVEQKPAEAP KPKESLADVT QKRRGLVIVK KKKDYEAPAP IKEEKKAEAA
190 200 210 220 230 240
VTNISDFKSM FSASDENLAR KKKKEKKVTV VSKKDSAEKM DLLGGSDFGD IVLEDEDVVV
250 260 270 280 290 300
LPDFSFKTPA PTPMQRTKQP NAMKTTVNNT INSFGEGGIQ RRARKKHKKP ENKQNSEAVT
310 320 330 340 350 360
SINIPKEIRV YEFAEKLNKQ PSEVIGKLFM LGMMTTKNDF LDEDAIEILA DEFNVEVNII
370 380 390 400 410 420
DDQKEFDYVA AYEEEIKDDE NLQPRAPVIT IMGHVDHGKT SLLDYIRKSR VAAGEAGGIT
430 440 450 460 470 480
QHVGAYMVNK NGRNITFIDT PGHEAFTAMR ARGAGVTDIV IIVVAADDGV KPQTKEAVSH
490 500 510 520 530 540
AKAAGVPIII AINKMDKESA NPDLVKTGLA ELDIMPTEWG GKYEFVPISA KTGMGIDDLL
550 560 570 580 590 600
EIVLLQADLL ELKANPKANA KATVIESSLQ KGRGPVATII VENGTLHVGD TVVAGVAYGK
610 620 630 640 650 660
IRSLLDDQGR SLREIKPGEC GVIVGLSEIA EAGETLIGVK TDKEAREYAQ KKAEYIRQKE
670 680 690 700 710 720
LSKSTKVSID ELSAKIAEGE LKTLPVIIKA DVGGSLEALK ASLEKLANDE IRVNVIHSGV
730 740 750 760 770 780
GGITQSDVAL ASASNDCIIL GFNIRPTGEI KEKAKESGVE IKTYNVIYNL IDDVKAILGG
790 800 810 820 830 840
LMSPIIREEQ LGQAQVRQVI HVPKVGTIAG CIVTEGTINR GAKIRLIREG VVVYEGLVSS
850 860 870 880
LKRFKDDVKE VAKGYECGVG IENFNDIREN DYIESFKEVK EKATL