Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A7Z8R4

Entry ID Method Resolution Chain Position Source
AF-A7Z8R4-F1 Predicted AlphaFoldDB

No variants for A7Z8R4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A7Z8R4

No associated diseases with A7Z8R4

No regional properties for A7Z8R4

Type Name Position InterPro Accession
No domain, repeats, and functional sites for A7Z8R4

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
phosphatidylinositol binding Binding to an inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
solute:proton antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(in) = solute(in) + H+(out).
ubiquitin binding Binding to ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation.

2 GO annotations of biological process

Name Definition
potassium ion transport The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
sodium ion transport The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDIFLVVLVL LTIIAISNIV NRFVPFIPVP LIQVALGIIA ASFPQGLHFE LNTELFFVLF
70 80 90 100 110 120
IAPLLFNDGK RTPRAELWNL RAPILLLALG LVFATVIVGG YTIHWMIPSI PLAAAFGLAA
130 140 150 160 170 180
ILSPTDVVAV SALSGRVKMP KGILRLLEGE GLMNDASGLV AFKFAIAAAV TGAFSLAQAA
190 200 210 220 230 240
FSFVLISAGG LLSGVVISFL IIRFRLFLRR LGMQDVTMHM LIQILTPFVI YLAAEEIGVS
250 260 270 280 290 300
GILAVVAGGI THAVEQDRLE STMVKLQIVS SSTWNIILFI LNGLVFVILG AQIPDVVSVI
310 320 330 340 350 360
FNDTAFNNMM VIGYIIVITL TLMILRFLWV LFFWNGKWFF NKDQSIYKPG LRSTLLISVS
370 380 390 400 410 420
GVRGAVTLAG SFSIPYVLSD GSPFPERNLI LFLAAGVIMC TLVLATIVLP ILTDKPEDNV
430 440 450 460 470 480
KEKKVKLLTA RRKLIKAALT AIKENMNETN KTASFAVIAE YNEKMKNLRF QQFTVKNRTK
490 500 510 520 530 540
KDERKVRAQG IQAEQEELLR LIERGDIPEE TADSLQERFD ELEVLYTNPF KVGLSKKKLK
550 560 570 580 590 600
RLMYWIFFGE QKKPEMTILN EEGLIRATRV KTAKAAIESL KKHMTEENKD VTLAVISFYN
610 620 630 640 650 660
HLIFRLGHSY HEQNPSRRFE NQKLEIKLRA VQAIRNEIQT LFEEREISRD MSHELRQYIN
670
DVEAAMLDGD E