A7Z4X1

PR
Gene name
RBAM_016840
Protein name
8-amino-7-oxononanoate synthase 1
Names
AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase, Alpha-oxoamine synthase
Species
Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / LMG 26770 / FZB42) (Bacillus amyloliquefaciens subsp. plantarum)
KEGG Pathway
bay:RBAM_016840
EC number
2.3.1.47: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-117 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A7Z4X1

Entry ID Method Resolution Chain Position Source
AF-A7Z4X1-F1 Predicted AlphaFoldDB

No variants for A7Z4X1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A7Z4X1

No associated diseases with A7Z4X1

2 regional properties for A7Z4X1

Type Name Position InterPro Accession
binding_site Aminotransferase, class-II, pyridoxal-phosphate binding site 236 - 245 IPR001917
domain Aminotransferase, class I/classII 40 - 381 IPR004839

Functions

Description
EC Number 2.3.1.47 Transferring groups other than amino-acyl groups
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
8-amino-7-oxononanoate synthase activity Catalysis of the reaction: L-alanine + H(+) + pimelyl-CoA = 8-amino-7-oxononanoate + CO(2) + CoA.
glycine C-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + glycine = L-2-amino-3-oxobutanoate + CoA + H(+).
pyridoxal phosphate binding Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.

1 GO annotations of biological process

Name Definition
biotin biosynthetic process The chemical reactions and pathways resulting in the formation of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKEFEFLKAE LDKMKENKTW QQMKQIETKQ GPSVEVKGEN VIQLSSNNYL GLTSHPRLVE
70 80 90 100 110 120
AAKRAAEEFG AGTGSVRTIA GTFTMHNELE KKLANFKKTE AALVFQSGFT TNQGVLSSIL
130 140 150 160 170 180
TKEDIVISDE LNHASIIDGI RLTKADKKVY RHVDMDDLER VLKKSMNYRM RLIVTDGVFS
190 200 210 220 230 240
MDGNIAPLPD IVKLAEAYDA FVMVDDAHAS GVLGKNGRGT VNHFGLDGRV HIQVGTLSKA
250 260 270 280 290 300
IGVLGGYAAG SQVLIDYLRH KGRPFLFSTS HPPAVTAACI EAIDVLLEEP EHMEKLWENT
310 320 330 340 350 360
AYFKDKLVQM GLTLTKSETP IVPILIGEEE KAQALSDLLL TRGVFAQSIV YPTVAQGKAR
370 380 390
IRTIITAEHT NEELDRALEV IRSAAKELQL V