Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A7Z4T4

Entry ID Method Resolution Chain Position Source
AF-A7Z4T4-F1 Predicted AlphaFoldDB

No variants for A7Z4T4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A7Z4T4

No associated diseases with A7Z4T4

6 regional properties for A7Z4T4

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 217 - 386 IPR000795
domain Small GTP-binding protein domain 220 - 376 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 51 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 143 - 191 IPR006847-2
domain Translation initiation factor IF- 2, domain 3 492 - 607 IPR023115
domain Translation initiation factor IF-2, domain II 393 - 486 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAKMRVYEYA KAINVSSKEI LTALKNMDIV VNNHMAMLEE KTIKQLDAKF KKGGAGVTSQ
70 80 90 100 110 120
KPAETNKNKP QGINQQPAGN QPNKIRDGKK NDVQNNQFNK NKKNNNNNKN KNKRNHNNKN
130 140 150 160 170 180
QYQQKPLKPK KELPEKITFS GSLTVGALAE ELGKEPSELI KKLMLLGVMA TINQELDKDT
190 200 210 220 230 240
IELIASEYGV ETEEVIVLEE TELEKYEEAD KEEDLQIRPP VVTIMGHVDH GKTTLLDSIR
250 260 270 280 290 300
KTKVVEGEAG GITQHIGAYQ IEENGKKITF LDTPGHAAFT TMRARGAEVT DITILVVAAD
310 320 330 340 350 360
DGVMPQTVEA INHAKAAEVP IIVAVNKVDK ESANPDRVMQ ELTEYGLVPE AWGGETIFVP
370 380 390 400 410 420
LSALTGKGID ELVEMILLVS EVEELKANPN RQAKGTVIEA ELDKGRGSVA TLLVQTGTLN
430 440 450 460 470 480
VGDPIVVGNT FGRVRAMVND LGRRVKTAGP STPVEITGLN DVPQAGDQFL VFKDEKTARS
490 500 510 520 530 540
VGEARASKQL EEQRSDKAKL SLDDLFEQIK QGDVKDINLI VKADVQGSAE ALTAALQKIE
550 560 570 580 590 600
VEGVKVKIIH TGVGAITESD IILASASNAI VIGFNVRPDG NAKSTAEAEN VDIRLHRIIY
610 620 630 640 650 660
KVIEEIEAAM KGMLDPEYEE KVIGQVEVRQ TFKVSKIGTI AGGYVTDGHI TRDSGLRLIR
670 680 690 700 710
DGVVIFEGEV DVLKRFKDDV KEVSQGYECG ITIKKYNDIR EGDIIEAYVM QEIERK