A7Z4S2

PR
Gene name
pyrH
Protein name
Uridylate kinase
Names
UK, Uridine monophosphate kinase, UMP kinase, UMPK
Species
Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / LMG 26770 / FZB42) (Bacillus amyloliquefaciens subsp. plantarum)
KEGG Pathway
bay:RBAM_016350
EC number
2.7.4.22: Phosphotransferases with a phosphate group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

59-135 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A7Z4S2

Entry ID Method Resolution Chain Position Source
AF-A7Z4S2-F1 Predicted AlphaFoldDB

No variants for A7Z4S2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A7Z4S2

No associated diseases with A7Z4S2

1 regional properties for A7Z4S2

Type Name Position InterPro Accession
domain Aspartate/glutamate/uridylate kinase 7 - 217 IPR001048

Functions

Description
EC Number 2.7.4.22 Phosphotransferases with a phosphate group as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
UMP kinase activity Catalysis of the reaction: ATP + UMP = ADP + UDP.

2 GO annotations of biological process

Name Definition
'de novo' CTP biosynthetic process The chemical reactions and pathways resulting in the formation of cytidine 5'-triphosphate (CTP) from simpler components.
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEKPKYNRIV LKLSGEALAG EQGNGINPTV IQSIAKQVKE IAELDVEVAV VVGGGNLWRG
70 80 90 100 110 120
KTGSDLGMDR ATADYMGMLA TVMNSLALQD SLETLGIQSR VQTSIEMRQV AEPYIRRKAI
130 140 150 160 170 180
RHLEKKRVVI FAAGTGNPYF STDTTAALRA AEIEADVILM AKNNVDGVYN ADPRKDESAV
190 200 210 220 230
KYEKLSYLDV LKDGLEVMDS TASSLCMDND IPLIVFSIME EGNIKRAVIG ESIGTIVRGK