A7Y2W8

PR
Gene name
slc6a9
Protein name
Sodium- and chloride-dependent glycine transporter 1
Names
GlyT-1, GlyT1, xGlyT1, Solute carrier family 6 member 9
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-49 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A7Y2W8

Entry ID Method Resolution Chain Position Source
AF-A7Y2W8-F1 Predicted AlphaFoldDB

No variants for A7Y2W8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A7Y2W8

No associated diseases with A7Y2W8

2 regional properties for A7Y2W8

Type Name Position InterPro Accession
domain Non-structural maintenance of chromosome element 4, C-terminal 294 - 383 IPR014854
domain Nse4/EID protein, Nse3/MAGE-binding domain 144 - 196 IPR029225

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
glycine:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + Na+(out) = glycine(in) + Na+(in).

2 GO annotations of biological process

Name Definition
neurotransmitter transport The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.
regulation of synaptic transmission, glycinergic Any process that modulates the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGLCVNGAVP SEATKKDENL KRGNWGNQIE FVLTSVGYAV GLGNVWRFPY LCYRNGGGAF
70 80 90 100 110 120
MFPYFIMLIF CGIPLFFMEL SFGQFASQGC LGVWRVSPIF KGVGYGMMVV STYIGIYYNV
130 140 150 160 170 180
VICIAFYYFF ASMNRVLPWT YCNNLWNTNN CAGVLSPNSS ASFNLSSQQN LLNLTLGLNQ
190 200 210 220 230 240
TLKRTSPSEE YWRRHVLKIS EDIGDFGEVQ LPLLGCLGVS WLVVFLCLIR GVKSSGKVVY
250 260 270 280 290 300
FTATFPYVVL TILFIRGITL EGAINGILYY LTPQWDKILH AMVWGDAASQ IFYSLGCAWG
310 320 330 340 350 360
GLITMASYNK FHNNCYRDSI IISITNCATS VYAGFVIFSI LGFMATHLGV DVSEVADHGP
370 380 390 400 410 420
GLAFVAYPEA LTLLPISPLW SILFFFMLIL LGLGTQFCLL ETLVTAVVDE IGNDWIIRWK
430 440 450 460 470 480
TLVTLGVAII GFLLGIPLTT QAGIYWLLLM DNYAASFSLV IISCIMCIAV MYIYGHRKYF
490 500 510 520 530 540
KDIEMMLGFP PPLFFQICWR FISPGIIFFI LIFTVIQYRP IQYNDYLYPD WAITIGFLMA
550 560 570 580 590 600
LSSVICIPLY AIFKIWCSEG DTFLQRLKNA VKPSKDWGPA LQEHRTGRYA QMSSTRSESN
610 620 630
PEAQPLNPEK MKEDLSLTIQ GSNGQAHTQD SKV