A7X4S6

PR
Gene name
yidC
Protein name
Membrane protein insertase YidC
Names
Foldase YidC, Membrane integrase YidC, Membrane protein YidC
Species
Staphylococcus aureus (strain Mu3 / ATCC 700698)
KEGG Pathway
saw:SAHV_2075
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

55-144 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A7X4S6

Entry ID Method Resolution Chain Position Source
AF-A7X4S6-F1 Predicted AlphaFoldDB

No variants for A7X4S6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A7X4S6

No associated diseases with A7X4S6

4 regional properties for A7X4S6

Type Name Position InterPro Accession
domain Translation elongation factor P/YeiP, central 68 - 130 IPR001059
domain Translation elongation factor, KOW-like 4 - 62 IPR013185
conserved_site Translation elongation factor P/YeiP, conserved site 154 - 173 IPR013852
domain Elongation factor P, C-terminal 133 - 188 IPR015365

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
membrane insertase activity Binds transmembrane domain-containing proteins and mediates their integration into a membrane.

1 GO annotations of biological process

Name Definition
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKKKALLPLF LGIMVFLAGC DYSKPEKRSG FFYNTFVDPM KNVLDWLGNN LLNDNYGLAI
70 80 90 100 110 120
IILVLVIRII LLPFMLSNYK NSHMMRQKMK VAKPEVEKIQ EKVKRARTQE EKMAANQELM
130 140 150 160 170 180
QVYKKYDMNP IKSMLGCLPM LIQLPIIMGL YFVLKDQLVD GLFKYPHFLW FDLGRPDIWI
190 200 210 220 230 240
TIIAGVLYFI QAYVSSKTMP DEQRQMGYMM MVISPIMIIW ISLSSASALG LYWSVSAAFL
250 260 270 280
VVQTHFANIY YEKVAKKEVQ PFIEAYEREH NGGSNKKGKN TQVVSKKKKK