A7TT36

PR
Gene name
TRM8
Protein name
tRNA (guanine-N(7)-)-methyltransferase
Names
Transfer RNA methyltransferase 8, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase
Species
Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus)
KEGG Pathway
vpo:Kpol_269p6
EC number
2.1.1.33: Methyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-93 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A7TT36

Entry ID Method Resolution Chain Position Source
AF-A7TT36-F1 Predicted AlphaFoldDB

No variants for A7TT36

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A7TT36

No associated diseases with A7TT36

No regional properties for A7TT36

Type Name Position InterPro Accession
No domain, repeats, and functional sites for A7TT36

Functions

Description
EC Number 2.1.1.33 Methyltransferases
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
tRNA (guanine-N7-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N7-methylguanine.
tRNA binding Binding to a transfer RNA.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDLRNPNRDP NSRRVLYRTN KEENRKELKH VKIDESTLAQ EGKKLDLPKK RFYRQRAHSN
70 80 90 100 110 120
PFSDHQLDYP TSPDDMNWSK LFPHYYDSTT GKMTKDVTIA DIGCGFGGLL IDLSPAFPED
130 140 150 160 170 180
LILGMEIRVQ VTNYVEDRII ALRTNHAKDY QYQNINVIRG NAMKFLPNFF QRAQLSKMFF
190 200 210 220 230 240
CFPDPHFKQR KHKARIITNT LLSEYAYVLK DNGVIYTITD VEDLHNWMVK HLEEHPLFER
250 260 270 280
YDKEWEDNDK CVQIMRNATE EGKKVERKKG DKFVACFRRL PNPAIV