A7TRN7
Gene name |
GET2 |
Protein name |
Golgi to ER traffic protein 2 |
Names |
|
Species |
Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus) |
KEGG Pathway |
vpo:Kpol_411p4 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A7TRN7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A7TRN7-F1 | Predicted | AlphaFoldDB |
No variants for A7TRN7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A7TRN7 | |||||
No associated diseases with A7TRN7
No regional properties for A7TRN7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for A7TRN7 | |||
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| GET complex | An endoplasmic reticulum protein-containing complex that is conserved in eukaryotics and that mediates the insertion of tail-anchored proteins into the ER membrane. In yeast, includes Get1p, Get2p and Get3p proteins. |
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| protein insertion into ER membrane | The process that results in incorporation of a protein into an endoplasmic reticulum (ER) membrane. It depends on specific topogenic sequences of amino acids that ensure that a protein acquires the proper orientation during its insertion into the ER membrane. |
| vesicle-mediated transport | A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSSELSETEK | RKLIRERRQK | KFSNGGASAR | LNRITGQAEN | SQLDTESPLD | SKSSRETTPT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VTKVDSNTEE | MDELLENIAT | SPSNKVEKSQ | KKKEQATSPQ | ETIDPELEIF | KQLAENQQND |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VSTPDLFSML | RSMKDNMAKS | AATDTNPPLE | PVDQQLLDYN | NYLINNLKVW | SIIFKWCFFL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| IPYLFALTRS | EPISFLPEQF | SNPSNFFMIF | LSFEIVATSI | YFQKLQNIEK | SNKINGFQSN |
| 250 | 260 | 270 | 280 | 290 | |
| NKIVNLVSLI | PEGVLPVPDI | KGKVIMALQY | WDVFSMFLTD | ICFVLVMMGL | FKLI |