A7TQJ9

PR
Gene name
MEF2
Protein name
Ribosome-releasing factor 2, mitochondrial
Names
RRF2mt, Elongation factor G 2, mitochondrial, EF-G2mt, mEF-G 2
Species
Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus)
KEGG Pathway
vpo:Kpol_463p13
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

278-353 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A7TQJ9

Entry ID Method Resolution Chain Position Source
AF-A7TQJ9-F1 Predicted AlphaFoldDB

No variants for A7TQJ9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A7TQJ9

No associated diseases with A7TQJ9

8 regional properties for A7TQJ9

Type Name Position InterPro Accession
domain Elongation factor EFG, domain V-like 670 - 796 IPR000640
domain Translational (tr)-type GTP-binding domain 19 - 306 IPR000795
domain Translation elongation factor EFTu-like, domain 2 350 - 419 IPR004161
domain Small GTP-binding protein domain 20 - 167 IPR005225
domain Elongation factor G, domain III 451 - 521 IPR009022
conserved_site Tr-type G domain, conserved site 62 - 77 IPR031157
domain EFG, domain V 673 - 789 IPR035649
domain Elongation Factor G, domain II 447 - 520 IPR041095

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

2 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.

2 GO annotations of biological process

Name Definition
mitochondrial translation The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.
ribosome disassembly The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MFGFGIRQLR GYASKTDLSK IRNIGIIAHI DAGKTTTTER MLYYSGKTNR IGNVDQGDTV
70 80 90 100 110 120
TDYLPQERSR GITIQSAAIS FNWQNDHRIN LIDTPGHVDF TFEVIKSLKV LDGCVTILDA
130 140 150 160 170 180
VAGVEAQTEK VWKQSYGIPK ICYINKMDRV GSGYSRTVKE LMIKMNQRVV LANMPLFKLD
190 200 210 220 230 240
PVTNEQVFEG VLDVVNMKAL RWDSTDVNKV DIADIDKFDS SLLDELTKAR EAMVETLSEF
250 260 270 280 290 300
DENLVEHFLE DAEGDYLKVS PTILNSSIRK STLSQDITPI LCGSSFRNIG VQPLLDAVVN
310 320 330 340 350 360
YLPSPLEAKF PELNEDIPIS YDKRKGLLFD NNSEICVAFA FKVITDEIRG QLVFVRVYSG
370 380 390 400 410 420
TLKNGHSVYN STNGKTFKIN KPVIMHANKT EDVQSLSAGE IGVLTGSTVF GRIETGDTLI
430 440 450 460 470 480
SHSMVKDGLK SIERKGNLNL KINPIIIPPP VFSVYIEPKT LGNRKAMEAA LKILVTEDPS
490 500 510 520 530 540
LHVSQDEETS QTLLSGMGEL HLEIARDKLL NDLKAEVGIG KLMISYKETI NSTTNPVIYQ
550 560 570 580 590 600
DDIGYKFTIQ IEPLEGEEVR VDKDTATEAW YPLGVDNNYL IFEKSNKPGL GAVWKHQIPY
610 620 630 640 650 660
DVVINTIKSS CLASFQRGGK IGGYALHSCA VRIKGDFEVP YDATSSNEIL NITRKLIIKS
670 680 690 700 710 720
LQALHESSYS LLEPIMDVEI VVNQKFMGEV IQDLTGHHKA NILSIEDEHG LDYNNERSTL
730 740 750 760 770 780
NFKDIVDSQY LPPDITLNLA KLDNGGDRCK VIKAEAPLKE MVSYSNKLRS LTEGRGMVYM
790
NYHGMKKVTP ERLDDVLQG