A7TJY3

PR
Gene name
SEY1
Protein name
Protein SEY1
Names
Species
Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus)
KEGG Pathway
vpo:Kpol_1037p42
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

361-563 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A7TJY3

Entry ID Method Resolution Chain Position Source
AF-A7TJY3-F1 Predicted AlphaFoldDB

No variants for A7TJY3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A7TJY3

No associated diseases with A7TJY3

2 regional properties for A7TJY3

Type Name Position InterPro Accession
domain GB1/RHD3-type guanine nucleotide-binding (G) domain 35 - 265 IPR030386
domain Sey1/RHD3-like, three-helix bundle domain 334 - 739 IPR046758

Functions

Description
EC Number
Subcellular Localization
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
  • Enriched in the cortical ER
  • Concentrated in punctae along the ER tubules
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.

1 GO annotations of biological process

Name Definition
endoplasmic reticulum organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDSKEEAIQL ITEEKHFSDD ALAYFKTCIG GRDVGVNYHV ISVFGSQSSG KSTLLNILFN
70 80 90 100 110 120
TSFDTMDAQI KRQQTTKGIW VAHSNELLSN VDVNPEDKSD LFILDVEGSD GLERGEDQDF
130 140 150 160 170 180
ERKAALFAIS VSEVLIVNMW EQQIGLYQGN NMALLKTVFE VNLSLFGKNK NGHKVLLLFV
190 200 210 220 230 240
IRDHVGVTPI SSLRDTITTE LINLWETLSK PAECENKKLS DFFELQFVGL SHKLLQEERF
250 260 270 280 290 300
VQDVKSLGDH FIMKDNEDYY FKPEYHHNLP LDGWTLYAKN CWELIEENRD LDLPTQQILV
310 320 330 340 350 360
ARFKTEEILN DSLEVLKSKY DSNVDPVIKD KLKLIQELSV LKTECLDMYD QHASKYVSAV
370 380 390 400 410 420
YLEKRDELEA KIYLKFLETI TLFIDSVSQD IFLQLVEDVN SESSKEPIFS KRLSNSTEVA
430 440 450 460 470 480
KSKFEDIIEE FAAAKILSEE VKEEVVKRFE NDLKETSDKL RVTALQKLIT RSSKIINARI
490 500 510 520 530 540
KDVVPQLLSN PDVDVWDRIM DKFHSIFSST LIKYKLDDDT YDFQFGGEDE ENNSTYKSIR
550 560 570 580 590 600
VAAWKSLNDT IHDYLKEDTI CNILRDRFEL KFRYDDEDSP ILWKNEEEVD LAFRVAKEYA
610 620 630 640 650 660
FKIFDVLALI KTSDNVEVVP DINFHDSDEM YEDDLGIYHS AKFSHILNEV QKEKIQIQVR
670 680 690 700 710 720
RQINVTVLDA KRSMIKTTTH IPLWIYAIIV VLGWNEFMMV IRNPLFVTLT ILILVSFYFI
730 740 750 760 770
NKFDLWGPVK SVAQTAAGET IGTIKTKLRD FVLEEHEKTP KIQSEKSNSD SEKVVENEKS