Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A7SWD3

Entry ID Method Resolution Chain Position Source
AF-A7SWD3-F1 Predicted AlphaFoldDB

No variants for A7SWD3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A7SWD3

No associated diseases with A7SWD3

4 regional properties for A7SWD3

Type Name Position InterPro Accession
domain LIS1 homology motif 22 - 54 IPR006594
domain CTLH, C-terminal LisH motif 60 - 117 IPR006595
domain CRA domain 113 - 209 IPR013144
domain CTLH/CRA C-terminal to LisH motif domain 62 - 202 IPR024964

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
proteasome-mediated ubiquitin-dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
Wnt signaling pathway The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSFAEEVNRE EWMEKIGKLR FQRAEMNRLI MDYLVTEGYK EAAEKFRIES GTQPTAPLDS
70 80 90 100 110 120
LDDRIKIREA VQKGDLEQAV SMTNKLNPDI LDSNQQLYFH LQQQRLIELI REKDIEAAVE
130 140 150 160 170 180
FAQGQFSEQG QESGRYLEEL EQTMALLAFD NPEESPFGDL LHTSQRQKVA SELNAAILEA
190 200 210 220
EHKKTQPKLA NVLKLLLWAQ DELEGKKVKF PKMAEIASGT FEESR