Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A7S6A5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A7S6A5-F1 | Predicted | AlphaFoldDB |
No variants for A7S6A5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A7S6A5 | |||||
No associated diseases with A7S6A5
3 regional properties for A7S6A5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | SDA1, C-terminal domain | 404 - 537 | IPR007949-1 |
| domain | SDA1, C-terminal domain | 531 - 684 | IPR007949-2 |
| domain | SDA1, N-terminal | 68 - 119 | IPR012977 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| ribosomal large subunit biogenesis | A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis. |
| ribosomal large subunit export from nucleus | The directed movement of a ribosomal large subunit from the nucleus into the cytoplasm. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKERKSSKMP | NNLPQLQNLI | KRDSDSLIHT | CFALSQFLQQ | LRHYQSNLQI | FKLNPSHTSK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VLQELVMFLC | QVAHCYPGHL | GSLPQELKDL | LHKHHSVMDS | DLRMTLCRAL | ILLRNKDLIS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PTSILELFFE | LFRCNDKVLR | QVLYTHIVTD | IKNMNAKHKN | NKVNSTLQNF | MYTMLKDSNA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VAAKKSLDVL | IELYKRNVWK | DAKTVNVITT | ACFSPVPKIL | VAALKFFLGS | DEGSAGDDSD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SESDVSYLKF | EFLEMIMNSL | ASLLLPKHKK | KHKQTSVNFS | ALHLINDPQG | FSERLFKQLE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ASTGRFEVRI | MLMNLISRLI | GVHQLFVFNF | YPFLQRYLQP | HQREVTKLLM | FFSQASHDLV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| PPEVVEPGVR | TIVNNFVTER | NSHEVMAVGL | NAVREVCQRC | PLVMTDTLLQ | DLAQYKTSKD |
| 430 | 440 | 450 | 460 | 470 | 480 |
| KSVMMASQSL | IQLFRSVNPN | LLHKKDRGQP | TESREDSKPL | DYAAVEAKDY | IPGAELINYA |
| 490 | 500 | 510 | 520 | 530 | 540 |
| NSTIILLYAT | LIPDGWETDE | GCDDGSDEDG | WIDVQHSSDE | EQEDEDPSGE | NQEGEEDGQT |
| 550 | 560 | 570 | 580 | 590 | 600 |
| RAARISQMRI | LTDEDFKKIR | MKQLTKEVQP | KLGKKRKRAT | TTEEPQGSRN | ELVALENIEG |
| 610 | 620 | 630 | 640 | 650 | 660 |
| IYKKRKHDKA | SRLETVIAGR | QDRPKYGTKK | KAKMNEHAGT | SNKEKRRKKN | FMMMRHNKLV |
| 670 | 680 | ||||
| RGKTKRSFRD | KQIALRDSLL | KRKKSKI |