A7RX69
Gene name |
v1g27680 |
Protein name |
Metalloprotease TIKI homolog |
Names |
|
Species |
Nematostella vectensis (Starlet sea anemone) |
KEGG Pathway |
nve:5515928 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A7RX69
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A7RX69-F1 | Predicted | AlphaFoldDB |
No variants for A7RX69
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A7RX69 | |||||
No associated diseases with A7RX69
No regional properties for A7RX69
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for A7RX69 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| metalloendopeptidase activity | Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| negative regulation of Wnt signaling pathway | Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway. |
| proteolysis | The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAAFTLWILV | LNVFLLGFQA | RKLASNLKFP | IQKCDDSTPQ | KNFNSFLWLV | KRTPPAYFYG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TIHVPYTRVW | DFIPMNSKQA | FTASQHVYFE | LDLTDEKTMR | ALMKCQMLPS | GTMLRQTLPR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KMFKRLKSHL | RYIKRMIPKW | IKHRDQETSS | AGPYANKLYE | MLTKDWDKKR | PIWVMLMVNS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LTESDIKTRG | IPVLDQYLAL | EASRNHKLIG | AVENVDEQCK | PLNALNASQV | VFALNQSLHF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QERLRRGQVQ | VTYTTDDLID | HYNCGDLKSV | LFSTQTSLPT | LTVNSSLEQR | ERKRAQEIDQ |
| 310 | 320 | 330 | 340 | 350 | 360 |
| YFRNELIFQR | NKRMAQRVIT | LLNNHPEKDF | FFAFGAGHFL | GNHSIIDIMK | KHGYDVEYVK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| PEQELPSFKA | KKSLNTRRER | RKGCRGRRKK | SKRCQKKKKR | KRPDYSRVRL | LQVATRRWNP |
| 430 | 440 | 450 | 460 | 470 | |
| TRKPYPTKLS | EAPGARDISS | RKAAASCTPI | WTVSLALTCA | VTCLLTYSGF | R |