A7NCM8

PR
Gene name
grpE
Protein name
Protein GrpE
Names
HSP-70 cofactor
Species
Francisella tularensis subsp holarctica (strain FTNF002-00 / FTA)
KEGG Pathway
fta:FTA_1256
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-110 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A7NCM8

Entry ID Method Resolution Chain Position Source
AF-A7NCM8-F1 Predicted AlphaFoldDB

No variants for A7NCM8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A7NCM8

No associated diseases with A7NCM8

No regional properties for A7NCM8

Type Name Position InterPro Accession
No domain, repeats, and functional sites for A7NCM8

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
adenyl-nucleotide exchange factor activity Binds to and stimulates the hydrolysis and exchange of adenyl nucleotides by other proteins.
chaperone binding Binding to a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.
protein homodimerization activity Binding to an identical protein to form a homodimer.

1 GO annotations of biological process

Name Definition
protein folding The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSKQEKSNVE DKSLDIETAA QVETAQESAS GALEELSVEE QLERAKDTIK ELEDSCDQFK
70 80 90 100 110 120
DEALRAKAEM ENIRKRAERD VSNARKFGIE KFAKELLPVI DSIEQALKHE VKLEEAIAMK
130 140 150 160 170 180
EGIELTAKML VDILKKNGVE ELDPKGEKFD PNLHEAMAMI PNPEFEDNTI FDVFQKGYML
190
NGRIVRAAKV VIVKN