A7MZI2

PR
Gene name
pnp
Protein name
Polyribonucleotide nucleotidyltransferase
Names
Polynucleotide phosphorylase, PNPase
Species
Vibrio campbellii (strain ATCC BAA-1116)
KEGG Pathway
vha:VIBHAR_03393
EC number
2.7.7.8: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

660-710 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A7MZI2

Entry ID Method Resolution Chain Position Source
AF-A7MZI2-F1 Predicted AlphaFoldDB

No variants for A7MZI2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A7MZI2

No associated diseases with A7MZI2

9 regional properties for A7MZI2

Type Name Position InterPro Accession
domain Exoribonuclease, phosphorolytic domain 1 13 - 142 IPR001247-1
domain Exoribonuclease, phosphorolytic domain 1 326 - 459 IPR001247-2
domain S1 domain 622 - 693 IPR003029
domain K Homology domain 555 - 620 IPR004087
domain K Homology domain, type 1 560 - 616 IPR004088
domain Exoribonuclease, phosphorolytic domain 2 145 - 208 IPR015847-1
domain Exoribonuclease, phosphorolytic domain 2 462 - 532 IPR015847-2
domain Polyribonucleotide nucleotidyltransferase, RNA-binding domain 239 - 323 IPR015848
domain RNA-binding domain, S1 623 - 693 IPR022967

Functions

Description
EC Number 2.7.7.8 Nucleotidyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
polyribonucleotide nucleotidyltransferase activity Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.
RNA binding Binding to an RNA molecule or a portion thereof.

2 GO annotations of biological process

Name Definition
mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MFEKPVVKTF QYGNHTVTLE TGVIARQATA AVMVTMDDTA VFVSVVGKKE AVEGQDFFPL
70 80 90 100 110 120
TVNYQERTYA AGKIPGGFFK REGRPSEGET LTARLIDRPI RPLFPDAFKN EVQVIATVVS
130 140 150 160 170 180
VNPDVQPDIP TMIGTSAALA ISGIPFNGPI GAARVGHIDG QLVLNPSNTE LEASKLDLVV
190 200 210 220 230 240
AGTESAVLMV ESEADNLTEE EMLSAVVFGH DQQQAVIKAI NEFKAEVATP AWDWVAPAEN
250 260 270 280 290 300
TALVTKIAEL AEAKLVEAYQ ITEKMARYDR IHEIAGEVNE VLLAEDPEAN TKEIHTIFHD
310 320 330 340 350 360
LEKTVVRRSI IAGNPRIDGR EKDMVRALDV RTGVLPRTHG SSLFTRGETQ ALVTATLGTQ
370 380 390 400 410 420
RDAQIIDELT GERKDHFLLH YNFPPYCVGE TGFVGSPKRR EIGHGKLAKR GIAAVMPSVD
430 440 450 460 470 480
EFPYTVRVVS EITESNGSSS MASVCGTSLA LMDAGVPIKS SVAGIAMGLV KEGDDFVVLS
490 500 510 520 530 540
DILGDEDHLG DMDFKVAGTN TGITALQMDI KIEGITKEIM QIALNQAQGA RKHILSVMDE
550 560 570 580 590 600
AISGAREDIS EFAPRIHTMK ISAEKIKDVI GKGGAVIRAL TEETGTTIEI EDDGTIKIAA
610 620 630 640 650 660
TEGAAAKEAI RRIEEITAEV EVGRIYTGKV ARLADFGAFV TVLPGKDGLV HISQIAEKRV
670 680 690 700
EKVSDYLTEG QEVQVKVLEI DRQGRVRLSM KEAVEKPAEE ANDASEAKGE