A7MX17

PR
Gene name
hisC
Protein name
Histidinol-phosphate aminotransferase
Names
Imidazole acetol-phosphate transaminase
Species
Vibrio campbellii (strain ATCC BAA-1116)
KEGG Pathway
vha:VIBHAR_01832
EC number
2.6.1.9: Transaminases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

212-284 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A7MX17

Entry ID Method Resolution Chain Position Source
AF-A7MX17-F1 Predicted AlphaFoldDB

No variants for A7MX17

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A7MX17

No associated diseases with A7MX17

2 regional properties for A7MX17

Type Name Position InterPro Accession
binding_site Aminotransferase, class-II, pyridoxal-phosphate binding site 206 - 215 IPR001917
domain Aminotransferase, class I/classII 42 - 337 IPR004839

Functions

Description
EC Number 2.6.1.9 Transaminases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
histidinol-phosphate transaminase activity Catalysis of the reaction: L-histidinol-phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate.
pyridoxal phosphate binding Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.

1 GO annotations of biological process

Name Definition
histidine biosynthetic process The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEKLARKQVQ QLTPYLSARR IGGTGDVWLN ANESPFNNEY KTDFARLNRY SECQPKELIS
70 80 90 100 110 120
AYAAYAGVKP EQTLTSRGAD EGIELLIRAF CEPGEDAILY CPPTYGMYGI SAETIGVERK
130 140 150 160 170 180
TVPLTSDWQL ELAGIEANLD NVKLVFVCSP NNPTGNLVKR EDIVSLLEMT KDRAIVVMDE
190 200 210 220 230 240
AYIDFCPEAS TVDLLAQYPN LAILRTLSKA FALAGLRCGF TLANEELINV LLKVIAPYPV
250 260 270 280 290 300
PVPVAEIATQ ALSEAGLARA KFQVLDLNAN RAYLQVGLSM IPVLEVFEGW GNYLLVKFPD
310 320 330 340
GDGLFKAAWE TGIILRNSPI ENCVRISVGN RDECEKTLGF IRNYYA