A7MR36

PR
Gene name
aas
Protein name
Bifunctional protein Aas
Names
Species
Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii)
KEGG Pathway
esa:ESA_00472
EC number
2.3.1.40: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

143-227 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A7MR36

Entry ID Method Resolution Chain Position Source
AF-A7MR36-F1 Predicted AlphaFoldDB

No variants for A7MR36

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A7MR36

No associated diseases with A7MR36

3 regional properties for A7MR36

Type Name Position InterPro Accession
domain AMP-dependent synthetase/ligase domain 233 - 619 IPR000873
domain Phospholipid/glycerol acyltransferase 26 - 140 IPR002123
conserved_site AMP-binding, conserved site 370 - 381 IPR020845

Functions

Description
EC Number 2.3.1.40 Transferring groups other than amino-acyl groups
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase activity Catalysis of the reaction: acyl- + O-(2-acyl-sn-glycero-3-phospho)ethanolamine = + O-(1-beta-acyl-2-acyl-sn-glycero-3-phospho)ethanolamine.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
long-chain fatty acid [acyl-carrier-protein] ligase activity Catalysis of the reaction: ATP + an acid

2 GO annotations of biological process

Name Definition
fatty acid metabolic process +The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
phospholipid biosynthetic process The chemical reactions and pathways resulting in the formation of a phospholipid, a lipid containing phosphoric acid as a mono- or diester.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVLKFFRWLF RLLFRIQVYG DTGPLTQQRV LITPNHVSFL DGALMALFLP VRPVFAVYTS
70 80 90 100 110 120
ISQQWYMRAL KPLIDFVPLD PTKPMSVKQL VRLVGEGRPV VIFPEGRISI SGSLMKIYEG
130 140 150 160 170 180
AGFVAAKSQA TVIPVRIEGA ELTFFSRLKG LVKRRLFPRI SIHILPPTSI PMPDAPKARD
190 200 210 220 230 240
RRKMAGEMLH QVMMEARMAA RPRETLFEAL INAQKRYGES KSCLEDINFK PDTYRSLMMK
250 260 270 280 290 300
TLFVGRILDK YSAPREAIGL MLPNASISAA VIFGAVMRGR IPAMMNYTAG VQGLTSAITA
310 320 330 340 350 360
AQIKTIFTSR QFLDKGKLWH LSEQITSVRW VFLEDLKGEV TAKDKAWIFA HLLMPRLAQV
370 380 390 400 410 420
EQQPEDAALI LFTSGSEGNP KGVVHSHKSL LANVEQIRTI ADFTADDKFM SALPLFHSFG
430 440 450 460 470 480
LTVGLFTPLL TGAEVFLYPS PLHYRVVPEL VYDRNCTVIF GTSTFLGHYA RFAHPYDFHL
490 500 510 520 530 540
VRYVVAGAEK LQESTKQIWQ DKFGLRILEG YGVTECAPVV SINVPMAAKP GTVGRILPAM
550 560 570 580 590 600
DARLVEVPGI EQGGRLQLKG PNIMKGYLRV ENPGVLEAPA AENPQGVSEP GWYDTGDIVA
610 620 630 640 650 660
FDEQGFVQIQ GRAKRFAKIA GEMVSLEMVE SLALAVSPEK MHATAIKHDA AKGEALVLFT
670 680 690 700 710
TDPELTREKL AQQARSKGVP ELAVPRDIRF LKQLPLLGSG KPDFVSLKKL VDQEETHHA